Anti-JIP3抗体(ab4545)
Key features and details
- Goat polyclonal to JIP3
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-JIP3抗体
参阅全部 JIP3 一抗 -
描述
山羊多克隆抗体to JIP3 -
宿主
Goat -
特异性
This antibody is expected to recognise both human isoforms of this protein. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse
预测可用于: Rat, Cow, Human -
免疫原
Synthetic peptide:
MEIQMDEGGGVV
, corresponding to N terminal amino acids 2-13 of Human JIP3. -
常规说明
GenBank Accession Number – NP_055948; NP_203750. LocusLink ID - 23162 (human); 30957 (mouse). Gene Ontology terms - vesicle-mediated transport; kinesin complex; cytoplasm; kinesin binding; MAP-kinase scaffold activity; protein kinase binding; regulation of JNK cascade.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interations with the JNK-signaling components and motor proteins. -
序列相似性
Belongs to the JIP scaffold family. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 537598 Cow
- Entrez Gene: 23162 Human
- Entrez Gene: 30957 Mouse
- Entrez Gene: 302983 Rat
- Omim: 605431 Human
- SwissProt: Q9UPT6 Human
- SwissProt: Q9ESN9 Mouse
- Unigene: 207763 Human
see all -
别名
- C-jun-amino-terminal kinase-interacting protein 3 antibody
- FLJ00027 antibody
- Homolog of Drosophila Sunday driver 2 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab4545 尚未被引用在任何文献中。