Anti-ITGA11抗体(ab114113)
Key features and details
- Goat polyclonal to ITGA11
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-ITGA11抗体
参阅全部 ITGA11 一抗 -
描述
山羊多克隆抗体to ITGA11 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse
预测可用于: Rat
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免疫原
Synthetic peptide:
C-PTEEDLSHAPQRNH
, corresponding to C terminal amino acids 1047-1060 of Mouse ITGA11 (NP_795896.4). -
阳性对照
- Mouse skeletal muscle lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99.48% Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab114113 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab114113于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 133 kDa).
1 hour primary incubation is recommended for this product. |
| 说明 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 133 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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功能
Integrin alpha-11/beta-1 is a receptor for collagen. -
组织特异性
According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. -
序列相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
发展阶段
Strongly up-regulated in differentiating fetal muscle cells (in vitro). -
结构域
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 319480 Mouse
- Entrez Gene: 315744 Rat
- SwissProt: P61622 Mouse
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别名
- integrin a11 antibody
- Integrin alpha 11 antibody
- Integrin alpha-11 antibody
see all
图片
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Western blot - Anti-ITGA11 antibody (ab114113)Anti-ITGA11 antibody (ab114113) at 1 µg/ml + Mouse skeletal muscle lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 133 kDa
Observed band size: 140 kDa why is the actual band size different from the predicted?
Primary incubation: 1 hour
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab114113 被引用在 2 文献中.
- Marmotti A et al. Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells as a Potential Source for Cartilage and Bone Regeneration: AnIn VitroStudy. Stem Cells Int 2017:1732094 (2017). PubMed: 29358953
- Verma R et al. Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One 11:e0148906 (2016). PubMed: 26848974