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重组

重组Anti-IRF7抗体[S04-1E1] (ab317406)

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Western blot - Anti-IRF7 Antibody [S04-1E1] (ab317406)

    Key features and details

    • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
    • Rabbit monoclonal [S04-1E1] to IRF7
    • Suitable for: WB
    • Reacts with: Rat

    概述

    • 产品名称

      Anti-IRF7抗体[S04-1E1]
      参阅全部 IRF7 一抗

    • 描述

      兔单克隆抗体[S04-1E1] to IRF7

    • 宿主

      Rabbit

    • 经测试应用

      适用于: WBmore details

    • 种属反应性

      与反应: Rat
      预测可用于: Human

    • 免疫原

      Synthetic peptide corresponding to Human IRF7.
      Database link: Q92985

    • 阳性对照

      • WB: Rat brain lysate.

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab317406于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    1/1000 - 1/2000. Predicted molecular weight: 54 kDa.
    说明
    WB
    1/1000 - 1/2000. Predicted molecular weight: 54 kDa.

    靶标

    • 功能

      Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability.

    • 组织特异性

      Expressed predominantly in spleen, thymus and peripheral blood leukocytes.

    • 序列相似性

      Belongs to the IRF family.
      Contains 1 IRF tryptophan pentad repeat DNA-binding domain.

    • 翻译后修饰

      In response to a viral infection, phosphorylated on the C-terminal serine cluster. Phosphorylation, and subsequent activation is inhibited by vaccinia virus protein E3.
      TRAF6-mediated ubiquitination is required for IRF7 activation.

    • 细胞定位

      Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.
    • Information by UniProt

    • 数据库链接

      • 别名

        • IMD39 antibody
        • Interferon regulatory factor 7 antibody
        • Interferon regulatory factor 7H antibody
        • IRF 7 antibody
        • IRF 7A antibody
        • IRF 7H antibody
        • IRF-7 antibody
        • IRF7 antibody
        • IRF7_HUMAN antibody
        • IRF7A antibody
        • IRF7B antibody
        • IRF7C antibody
        • IRF7H antibody
        see all

      图片

      • Western blot - Anti-IRF7 Antibody [S04-1E1] (ab317406)
        Western blot - Anti-IRF7 Antibody [S04-1E1] (ab317406)
        Anti-IRF7 Antibody [S04-1E1] (ab317406) at 1/1000 dilution + rat brain lysate

        Predicted band size: 54 kDa

      实验方案

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      文献 (0)

      发表研究结果有使用 ab317406？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab317406 尚未被引用在任何文献中。

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