重组Anti-IPL-1/STK13/Aurora C抗体[EP1011Y] (ab46783)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP1011Y] to IPL-1/STK13/Aurora C
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-IPL-1/STK13/Aurora C抗体[EP1011Y]
参阅全部 IPL-1/STK13/Aurora C 一抗 -
描述
兔单克隆抗体[EP1011Y] to IPL-1/STK13/Aurora C -
宿主
Rabbit -
特异性
This antibody is not recommended in tissue lysate testing.
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经测试应用
适用于: WBmore details
不适用于: ICC/IF -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human IPL-1/STK13/Aurora C aa 1-100 (N terminal). The exact sequence is proprietary.
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阳性对照
- HepG2 cell lysate
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EP1011Y -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab46783于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
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说明 |
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WB
1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa). |
靶标
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功能
May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis. -
组织特异性
Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase. -
疾病相关
Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA. -
序列相似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Contains 1 protein kinase domain. -
细胞定位
Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis. - Information by UniProt
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数据库链接
- Entrez Gene: 6795 Human
- Omim: 603495 Human
- SwissProt: Q9UQB9 Human
- Unigene: 98338 Human
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别名
- AURKC antibody
- AIE 2 antibody
- Aie1 antibody
see all
图片
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Anti-IPL-1/STK13/Aurora C antibody [EP1011Y] (ab46783) at 1/1000 dilution + HepG2 lysate at 10 µg
Secondary
goat anti rabbit HRP
Predicted band size: 36 kDa
Observed band size: 36 kDa
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab46783 被引用在 1 文献中.
- Chen L et al. BRDT promotes ovarian cancer cell growth. Cell Death Dis 11:1021 (2020). PubMed: 33257688