Anti-Integrin alpha V抗体[RMV-7] (ab63490)
Key features and details
- Rat monoclonal [RMV-7] to Integrin alpha V
- Suitable for: IP, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG1
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-Integrin alpha V抗体[RMV-7]
参阅全部 Integrin alpha V 一抗 -
描述
大鼠单克隆抗体[RMV-7] to Integrin alpha V -
宿主
Rat -
经测试应用
适用于: IP, Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Integrin alpha V. Cultured LAK cells from Balb/c mice
Database link: P43406 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
RMV-7 -
骨髓瘤
P3x63-Ag8.653 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63490于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
1/10 - 1/100.
ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10 µl of the suggested working dilution to label 106 cells in 100µl. |
| 说明 |
|---|
|
IP
Use at an assay dependent concentration. |
|
Flow Cyt
1/10 - 1/100. ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10 µl of the suggested working dilution to label 106 cells in 100µl. |
靶标
-
功能
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. -
序列相似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 16410 Mouse
- SwissProt: P43406 Mouse
- Unigene: 227 Mouse
-
别名
- antigen identified by monoclonal antibody L230 antibody
- CD 51 antibody
- CD51 antibody
see all
实验方案
数据表及文件
-
Datasheet download
文献 (2)
ab63490 被引用在 2 文献中.
- Khalifeh-Soltani A et al. Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids. Nat Med 20:175-83 (2014). PubMed: 24441829
- Gupton SL et al. Mena binds a5 integrin directly and modulates a5ß1 function. J Cell Biol 198:657-76 (2012). IF . PubMed: 22908313
