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重组

重组Anti-Insulin degrading enzyme / IDE抗体[S04-4E8] (ab317428)

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Western blot - Anti-Insulin degrading enzyme / IDE Antibody [S04-4E8] (ab317428)

    Key features and details

    • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
    • Rabbit monoclonal [S04-4E8] to Insulin degrading enzyme / IDE
    • Suitable for: WB
    • Reacts with: Human

    概述

    • 产品名称

      Anti-Insulin degrading enzyme / IDE抗体[S04-4E8]
      参阅全部 Insulin degrading enzyme / IDE 一抗

    • 描述

      兔单克隆抗体[S04-4E8] to Insulin degrading enzyme / IDE

    • 宿主

      Rabbit

    • 经测试应用

      适用于: WBmore details

    • 种属反应性

      与反应: Human

    • 免疫原

      Synthetic peptide corresponding to Human Insulin degrading enzyme/ IDE.
      Database link: P14735

    • 阳性对照

      • WB: A549, HL-60 and U2OS cell lysate.

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab317428于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    1/2000 - 1/10000. Predicted molecular weight: 118 kDa.
    说明
    WB
    1/2000 - 1/10000. Predicted molecular weight: 118 kDa.

    靶标

    • 功能

      Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

    • 序列相似性

      Belongs to the peptidase M16 family.

    • 翻译后修饰

      The N-terminus is blocked.

    • 细胞定位

      Cytoplasm. Cell surface. Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
    • Information by UniProt

    • 数据库链接

      • 别名

        • Abeta-degrading protease antibody
        • FLJ35968 antibody
        • Ide antibody
        • IDE_HUMAN antibody
        • Insulin protease antibody
        • Insulin-degrading enzyme antibody
        • Insulinase antibody
        • Insulysin antibody
        • OTTHUMP00000020097 antibody
        see all

      图片

      • Western blot - Anti-Insulin degrading enzyme / IDE Antibody [S04-4E8] (ab317428)
        Western blot - Anti-Insulin degrading enzyme / IDE Antibody [S04-4E8] (ab317428)
        All lanes : Anti-Insulin degrading enzyme / IDE Antibody [S04-4E8] (ab317428) at 1/1000 dilution

        Lane 1 : A549 cell lysate
        Lane 2 : HL-60 cell lysate
        Lane 3 : U2OS cell lysate

        Predicted band size: 118 kDa

      实验方案

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      文献 (0)

      发表研究结果有使用 ab317428？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab317428 尚未被引用在任何文献中。

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