Anti-Influenza Virus NS1A Binding蛋白抗体(ab127566)
Key features and details
- Rabbit polyclonal to Influenza Virus NS1A Binding Protein
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-Influenza Virus NS1A Binding蛋白抗体
参阅全部 Influenza Virus NS1A Binding Protein 一抗 -
描述
兔多克隆抗体to Influenza Virus NS1A Binding蛋白 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment, corresponding to a region within amino acids 415-600 of Human Influenza Virus NS1A Binding Protein (Q9Y6Y0).
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阳性对照
- NT2D1, IMR32, U-87 MG and MCF7 whole cell lysates; Human Huh7 xenograft and Mouse muscle tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab127566于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 72 kDa.
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| IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 72 kDa. |
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IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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相关性
NS1ABP plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats and is known to protect cells from cell death induced by actin destabilization. Interacts with NS/Influenza virus NS1A protein and is believed to mediate the inhibition of its splicing activity. It is usually associated with actin filaments (related to speckle domains) but following Influenza Avirus infection, NS1ABP presents a more diffuse distribution in the nucleoplasm -
细胞定位
Nuclear -
数据库链接
- Entrez Gene: 10625 Human
- Entrez Gene: 117198 Mouse
- Omim: 609209 Human
- SwissProt: Q9Y6Y0 Human
- SwissProt: Q920Q8 Mouse
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别名
- Aryl hydrocarbon receptor associated 3 antibody
- DKFZp686K06216 antibody
- FLARA 3 antibody
see all
图片
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Western blot - Anti-Influenza Virus NS1A Binding Protein antibody (ab127566)Anti-Influenza Virus NS1A Binding Protein antibody (ab127566) at 1/1000 dilution + U-87 MG whole cell lysate at 30 µg
Predicted band size: 72 kDa
7.5% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Influenza Virus NS1A Binding Protein antibody (ab127566)ab127566, at 1/500 dilution, staining Influenza Virus NS1A Binding Protein in Human Huh7 xenograft tissue by Immunohistochemistry. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Influenza Virus NS1A Binding Protein antibody (ab127566)ab127566, at 1/500 dilution, staining Influenza Virus NS1A Binding Protein in paraffin-embedded Mouse muscle tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab127566 被引用在 2 文献中.
- Chen K et al. An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma. Onco Targets Ther 14:1589-1604 (2021). PubMed: 33688206
- Chen HY et al. KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination. Oncogene 34:5141-51 (2015). PubMed: 25619834