Anti-IMPG1抗体(ab113493)
Key features and details
- Rabbit polyclonal to IMPG1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IMPG1抗体 -
描述
兔多克隆抗体to IMPG1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment, corresponding to amino acids 217-437 of Human IMPG1 (BC117450).
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阳性对照
- Human fetal liver, fetal muscle, Fetal kidney, HepG2, 97 H, and LO2 cell lysates; Human fetal liver tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab113493 is purified by a peptide affinity column. -
克隆
多克隆 -
同种型
IgG
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab113493于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 89 kDa.
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| IHC-P |
1/100 - 1/500.
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 89 kDa. |
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IHC-P
1/100 - 1/500. |
靶标
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功能
May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix. -
组织特异性
Abundantly expressed in retina where it is specifically expressed by cone and rod photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina. -
序列相似性
Contains 2 SEA domains. -
翻译后修饰
The N-terminus is blocked.
Highly glycosylated (N- and O-linked carbohydrates and sialic acid). -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 3617 Human
- Entrez Gene: 63859 Mouse
- Entrez Gene: 66014 Rat
- Omim: 602870 Human
- SwissProt: Q17R60 Human
- SwissProt: Q8R1W8 Mouse
- SwissProt: Q9ET62 Rat
- Unigene: 590893 Human
see all -
别名
- IPM150 antibody
- GP147 antibody
- IMPG1 antibody
see all
图片
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Western blot - Anti-IMPG1 antibody (ab113493)All lanes : Anti-IMPG1 antibody (ab113493) at 1/500 dilution
Lane 1 : Human fetal liver lysate
Lane 2 : Human fetal muscle lysate
Lane 3 : Human fetal kidney lysate
Lane 4 : HepG2 cell lysate
Lane 5 : 97 H cell lysate
Lane 6 : LO2 cell lysate
Predicted band size: 89 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IMPG1 antibody (ab113493)ab113493 at 1/100 dilution staining IMPG1 in Formalin-fixed, Paraffin-embedded Human fetal liver tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab113493 被引用在 1 文献中.
- Felemban M et al. Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix. Acta Biomater 74:207-221 (2018). PubMed: 29777959