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AB25034

Anti-IL-5 抗体 [QS-5]

Anti-IL-5 antibody [QS-5]

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(4 Publications)

Mouse Monoclonal IL-5 antibody. Suitable for ELISA, WB, FuncS (Neut/Block), ELISPOT, IHC-Fr and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL5.

查看别名

Interleukin-5, IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF, IL5

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

QS-5

亚型

IgG1

不含载体蛋白

No

反应种属

Human

应用

WB, ELISA, IHC-Fr, FuncS (Neut/Block), ELISPOT

applications

免疫原

Recombinant Full Length Protein corresponding to Human IL5.

P05113

特异性

Binds with high efficiency to natural and recombinant human IL5.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"}, "ELISPOT" : {"fullname" : "ELISPOT", "shortname":"ELISPOT"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>", "ELISPOT-species-checked": "guaranteed", "ELISPOT-species-dilution-info": "", "ELISPOT-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Ion exchange chromatography
存储溶液
Constituents: PBS, 4.275% Trehalose
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed : 2653458, PubMed : 9010276). Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB (PubMed : 1495999, PubMed : 22528658). Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (PubMed : 7613138).
See full target information IL5

文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Experimental dermatology 27:1328-1335 PubMed30230040

2018

Down-regulated SHARPIN may accelerate the development of atopic dermatitis through activating interleukin-33/ST2 signalling.

Applications

Unspecified application

Species

Unspecified reactive species

Lingjie Tang,Jiaman Wang,Jingna Zhu,Yanhua Liang

The Journal of allergy and clinical immunology 142:1489-1499.e23 PubMed30102935

2018

IgD-activated mast cells induce IgE synthesis in B cells in nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Guan-Ting Zhai,Hai Wang,Jing-Xian Li,Ping-Ping Cao,Wen-Xiu Jiang,Jia Song,Yin Yao,Zhi-Chao Wang,Zhe-Zheng Wang,Meng-Chen Wang,Bo Liao,Qi-Miao Feng,Xiang Lu,Heng Wang,Peisong Gao,Zheng Liu

International forum of allergy & rhinology 4:453-62 PubMed24504744

2014

Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Daishi Chen,Mingfeng Mao,Luisa M Bellussi,Desiderio Passali,Lei Chen

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 32:386-92 PubMed23349558

2013

The role of High Mobility Group Box 1 chromosomal protein in the pathogenesis of chronic sinusitis and nasal polyposis.

Applications

IHC

Species

Unspecified reactive species

L M Bellussi,L Chen,D Chen,F M Passali,D Passali
View all publications

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