重组Anti-IL-3RB抗体[EP1037Y] (ab52609)
![Western blot - Anti-IL-3RB antibody [EP1037Y] (ab52609)](https://www.abcam.cn/ps/products/52/ab52609/Images/ab52609-510428-anti-il-3rb-antibody-ep1037y-western-blot-human-il3rb.jpg "Western blot - Anti-IL-3RB antibody [EP1037Y] (ab52609)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP1037Y] to IL-3RB
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
-
产品名称
Anti-IL-3RB抗体[EP1037Y]
参阅全部 IL-3RB 一抗 -
描述
兔单克隆抗体[EP1037Y] to IL-3RB -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
阳性对照
- WB: Human Recombinant IL3RB Protein.
-
常规说明
This product has switched from a hybridoma to recombinant production method on 25th May 2023.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EP1037Y -
同种型
IgG -
研究领域
相关产品
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab52609于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/20000. Predicted molecular weight: 130 kDa.
|
| 说明 |
|---|
|
WB
1/20000. Predicted molecular weight: 130 kDa. |
靶标
-
功能
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. -
序列相似性
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 2 fibronectin type-III domains. -
结构域
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 1439 Human
- Omim: 138981 Human
- SwissProt: P32927 Human
- Unigene: 592192 Human
-
别名
- Beta-C antibody
- CD131 antibody
- CDw131 antibody
see all
图片
-
Western blot - Anti-IL-3RB antibody [EP1037Y] (ab52609)Anti-IL-3RB antibody [EP1037Y] (ab52609) at 1/20000 dilution + Human Recombinant IL3RB Protein (full length), 15 ng
Secondary
Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/20000 dilution
Predicted band size: 130 kDa
Observed band size: 130 kDa
Exposure time: 5 secondsBlocking and diluting buffer: 5% NFDM/TBST.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab52609 被引用在 2 文献中.
- Medana IM et al. Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria. Malar J 8:261 (2009). IHC-P ; Human . PubMed: 19930602
- Schroeder JT et al. Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease. J Immunol 182:2432-8 (2009). PubMed: 19201898