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AB113498

Anti-IL-31RA 抗体

Anti-IL-31RA antibody

0

(1 Review)

|

(9 Publications)

Rabbit Polyclonal IL-31RA antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human IL31RA aa 50-400.

查看别名

CRL3, GPL, UNQ6368/PRO21073/PRO21384, IL31RA, Interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, ZcytoR17, hGLM-R, Gp130-like receptor

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-31RA antibody (AB113498)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-31RA antibody (AB113498)

ab113498, at 1/100, staining IL31RA in Formalin-fixed, Paraffin-embedded Human fetal prostate tissue by Immunohistochemistry.

Western blot - Anti-IL-31RA antibody (AB113498)
  • WB

Unknown

Western blot - Anti-IL-31RA antibody (AB113498)

All lanes:

Western blot - Anti-IL-31RA antibody (ab113498) at 1/500 dilution

Lane 1:

Jurkat cell lysate

Lane 2:

Human fetal liver lysate

Lane 3:

Human fetal kidney lysate

Lane 4:

Human fetal spleen lysate

Lane 5:

Human fetal colon lysate

Predicted band size: 83 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB, IHC-P

applications

免疫原

Recombinant Fragment Protein within Human IL31RA aa 50-400. The exact immunogen used to generate this antibody is proprietary information.

Q8NI17

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

性能和储存信息

形式
Lyophilized
复溶
Reconstitute in 200 µL of water
纯化工艺
Affinity purification Immunogen
纯化说明
ab113498 is purified by a protein affinity column.
存储溶液
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: 1% BSA
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed : 11877449, PubMed : 14504285, PubMed : 15194700, PubMed : 15627637). May function in skin immunity (PubMed : 15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
See full target information IL31RA

文献 (9)

Recent publications for all applications. Explore the full list and refine your search

Experimental dermatology 32:1412-1419 PubMed37260420

2023

Divergent in situ expression of IL-31 and IL-31RA between bullous pemphigoid and pemphigus vulgaris.

Applications

Unspecified application

Species

Unspecified reactive species

Ecem Zeliha Ergun,Rui Aoki,Orsolya N Horváth,Daniela Hartmann,Takashi K Satoh,Laura Calabrese,Ayşe Esra Koku Aksu,Mehmet Salih Gürel,Vildan Manav,Michael J Flaig,Miklós Sárdy,Thomas Ruzicka,Lars E French,Işın Sinem Bağcı

International journal of molecular sciences 24: PubMed37047440

2023

Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Sandra Tejedor,Marc Buigues,Hernán González-King,Andreia M Silva,Nahuel Aquiles García,Niek Dekker,Pilar Sepúlveda

The Journal of dermatology 50:927-930 PubMed36651089

2023

IL-31 and IL-31 receptor alpha in pemphigus: Contributors to more than just itch?

Applications

Unspecified application

Species

Unspecified reactive species

Satoshi Okuno,Takashi Hashimoto,Yuki Yamazaki,Manami Okuzawa,Takahiro Satoh

PloS one 16:e0246630 PubMed33539470

2021

Prenylated quinolinecarboxylic acid compound-18 prevents sensory nerve fiber outgrowth through inhibition of the interleukin-31 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Masato Ogura,Kumiko Endo,Toshiyuki Suzuki,Yoshimi Homma

Experimental dermatology 30:804-810 PubMed33428793

2021

Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta.

Applications

Unspecified application

Species

Unspecified reactive species

Takashi Hashimoto,Leigh A Nattkemper,Hei Sung Kim,Christina D Kursewicz,Emilie Fowler,Serena M Shah,Sonali Nanda,Rachel A Fayne,John F Paolini,Paolo Romanelli,Gil Yosipovitch

Acta dermato-venereologica 101:adv00375 PubMed33236123

2021

Dermal Periostin: A New Player in Itch of Prurigo Nodularis.

Applications

Unspecified application

Species

Unspecified reactive species

Takashi Hashimoto,Leigh A Nattkemper,Hei Sung Kim,Christina D Kursewicz,Emilie Fowler,Serena M Shah,Sonali Nanda,Rachel A Fayne,Paolo Romanelli,Gil Yosipovitch

The Journal of investigative dermatology 140:850-859.e3 PubMed31626785

2019

Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Takashi Hashimoto,Christina Dorothy Kursewicz,Rachel Alison Fayne,Sonali Nanda,Serena Maya Shah,Leigh Nattkemper,Hiroo Yokozeki,Gil Yosipovitch

Journal of the American Academy of Dermatology 83:53-62 PubMed31351883

2019

Pathophysiologic mechanisms of itch in bullous pemphigoid.

Applications

Unspecified application

Species

Unspecified reactive species

Takashi Hashimoto,Christina Dorothy Kursewicz,Rachel Alison Fayne,Sonali Nanda,Serena Maya Shah,Leigh Nattkemper,Hiroo Yokozeki,Gil Yosipovitch

The British journal of dermatology 181:1079-1081 PubMed31049931

2019

CD11b cells markedly express the itch cytokine interleukin-31 in polymorphic light eruption.

Applications

Unspecified application

Species

Unspecified reactive species

V Patra,J Strobl,A Gruber-Wackernagel,P Vieyra-Garcia,G Stary,P Wolf
View all publications

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