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AB242971

重组Anti-IL-23抗体[EPR19069-180] - BSA and Azide free (Capture)

Anti-IL-23 antibody [EPR19069-180] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal IL-23 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

查看别名

SGRF, UNQ2498/PRO5798, IL23A, Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19

1 Images
ELISA - Anti-IL-23 antibody [EPR19069-180] - BSA and Azide free (Capture) (AB242971)
  • ELISA

Supplier Data

ELISA - Anti-IL-23 antibody [EPR19069-180] - BSA and Azide free (Capture) (AB242971)

Example of Human IL-23 standard curve. Background-subtracted data values (mean +/- SD) are graphed.

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR19069-180

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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搭配使用产品

Assay Kits

AB221837

Human IL-23 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human IL-23 ELISA Kit (AB221837)

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  • 0
Sample Prep & Detection Kits

AB188288

Cy5® Conjugation Kit (Fast) - Lightning-Link®

Immunocytochemistry - Cy5® Conjugation Kit (Fast) - Lightning-Link® (AB188288)

  • 5
  • 1
Sample Prep & Detection Kits

AB218260

Oligonucleotide Conjugation Kit

Conjugation - Oligonucleotide Conjugation Kit (AB218260)

  • 0
  • 0
Primary Antibodies

AB243020

Anti-IL-12B antibody [EPR20096-81] - BSA and Azide free (Capture/Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-12B antibody [EPR20096-81] - BSA and Azide free (Capture/Detector) (AB243020)

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Primary Antibodies

AB242609

Anti-IL-17A antibody [EPR19941-88] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-17A antibody [EPR19941-88] - BSA and Azide free (Capture) (AB242609)

  • 0
  • 0
Primary Antibodies

AB233396

Anti-CD69 antibody [EPR21814]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD69 antibody [EPR21814] (AB233396)

  • 5
  • 4
Primary Antibodies

AB316783

Anti-CXCL17/DMC antibody [EPR22655-183] - BSA and Azide free (Capture)

Recombinant|RabMAb

Sandwich ELISA - Anti-CXCL17/DMC antibody [EPR22655-183] - BSA and Azide free (Capture) (AB316783)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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产品详情

ab242971 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human IL-23. The recommended pair for sandwich ELISA is:
Capture: ab242971, Human IL-23 Capture Antibody (unconjugated)
Detector: ab243020, Human IL-23 Detector Antibody (unconjugated)
The reference range value is 15.62 - 1000 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity (PubMed : 11114383). Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4 (PubMed : 29287995, PubMed : 32474165, PubMed : 33606986). This process leads to activation of several pathways including p38 MAPK or NF-kappa-B and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A (PubMed : 12023369). In turn, participates in the early and effective intracellular bacterial clearance (PubMed : 32474165). Promotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells (PubMed : 17676044).
See full target information IL23A
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Abcam Product Promise

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详情请参阅我们的条款与条件。

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