Anti-IL-22抗体[IMG8F11E2] (ab134035)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22 antibody [IMG8F11E2] (ab134035)](https://www.abcam.cn/ps/products/134/ab134035/Images/ab134035-148125-anti-il-22-antibody-img8f11e2-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22 antibody [IMG8F11E2] (ab134035)")
Key features and details
- Mouse monoclonal [IMG8F11E2] to IL-22
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG1
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-IL-22抗体[IMG8F11E2]
参阅全部 IL-22 一抗 -
描述
小鼠单克隆抗体[IMG8F11E2] to IL-22 -
宿主
Mouse -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human IL-22.
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阳性对照
- Recombinant Human IL22; Human spleen cell lysate; Human brain and kidney tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituent: 99.95% PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
IMG8F11E2 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab134035于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 20 kDa.
|
|
| IHC-P | (1) |
Use a concentration of 5 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 20 kDa. |
|
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
Cytokine that contributes to the inflammatory response in vivo. -
序列相似性
Belongs to the IL-10 family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 50616 Human
- Omim: 605330 Human
- SwissProt: Q9GZX6 Human
- Unigene: 287369 Human
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别名
- Cytokine Zcyto18 antibody
- IL 10 related T cell derived inducible factor antibody
- IL 21 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22 antibody [IMG8F11E2] (ab134035)Immunohistochemical analysis of Paraffin-embedded Human brain tissue (top) and Human kidney tissue (bottom) labelling IL22 with ab134035 at 5µg/ml.
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![Western blot - Anti-IL-22 antibody [IMG8F11E2] (ab134035)](https://www.abcam.cn/ps/products/134/ab134035/Images/ab134035-148126-anti-il-22-antibody-img8f11e2-western-blot.jpg)
Western blot - Anti-IL-22 antibody [IMG8F11E2] (ab134035)All lanes : Anti-IL-22 antibody [IMG8F11E2] (ab134035) at 1 µg/ml
Lane 1 : Recombinant Human IL22 protein
Lane 2 : Human spleen cell lysate
Secondary
All lanes : Goat anti-mouse HRP
Developed using the ECL technique.
Predicted band size: 20 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab134035 被引用在 3 文献中.
- Liu B et al. Reciprocal regulation of interleukin-17A and interleukin-22 secretion through aryl hydrocarbon receptor activation in CD4+ T cells of patients with vitiligo. Exp Ther Med 21:158 (2021). PubMed: 33456525
- Zeng C et al. The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation. Cell Mol Biol Lett 26:7 (2021). PubMed: 33622250
- Orfali RL et al. Staphylococcus aureus enterotoxins modulate IL-22-secreting cells in adults with atopic dermatitis. Sci Rep 8:6665 (2018). PubMed: 29703987