Anti-IL-20R2抗体(ab124332)
Key features and details
- Rabbit polyclonal to IL-20R2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-IL-20R2抗体
参阅全部 IL-20R2 一抗 -
描述
兔多克隆抗体to IL-20R2 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Human IL-20R2 aa 30-231.
-
阳性对照
- Human fetal testis tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Lyophilized:Reconstitute in 200µl sterile H2O. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124332于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/100 - 1/500.
|
说明 |
---|
IHC-P
1/100 - 1/500. |
靶标
-
功能
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. -
组织特异性
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. -
序列相似性
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 53833 Human
- Entrez Gene: 213208 Mouse
- Entrez Gene: 501043 Rat
- Omim: 605621 Human
- SwissProt: Q6UXL0 Human
- Unigene: 61232 Human
-
别名
- DIRS1 antibody
- Fibronectin type III domain containing 6 antibody
- FNDC6 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (4)
ab124332 被引用在 4 文献中.
- Ónody A et al. Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases. J Transl Med 19:237 (2021). PubMed: 34078403
- Pap D et al. Characterization of IL-19, -20, and -24 in acute and chronic kidney diseases reveals a pro-fibrotic role of IL-24. J Transl Med 18:172 (2020). PubMed: 32306980
- An W et al. Exogenous IL-19 attenuates acute ischaemic injury and improves survival in male mice with myocardial infarction. Br J Pharmacol N/A:N/A (2018). PubMed: 30460984
- Steinert A et al. The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models. J Immunol 199:2570-2584 (2017). PubMed: 28864472