Anti-IL-2 Receptor alpha抗体[B-G3] - BSA and Azide free (ab27308)
![Flow Cytometry - Anti-IL-2 Receptor alpha antibody [B-G3] (ab27308)](https://www.abcam.cn/ps/products/27/ab27308/Images/ab27308-38050-anti-il-2-receptor-alpha-antibody-b-g3-flow-cytometry.gif "Flow Cytometry - Anti-IL-2 Receptor alpha antibody [B-G3] (ab27308)")
Key features and details
- Mouse monoclonal [B-G3] to IL-2 Receptor alpha - BSA and Azide free
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-IL-2 Receptor alpha抗体[B-G3] - BSA and Azide free
参阅全部 IL-2 Receptor alpha 一抗 -
描述
小鼠单克隆抗体[B-G3] to IL-2 Receptor alpha - BSA and Azide free -
宿主
Mouse -
特异性
This antibody recognises both soluble and membrane bound human IL-2 Receptor alpha chain. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human IL-2 Receptor alpha. PHA activated T cells
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阳性对照
- PHA activated lymphocytes
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常规说明
This antibody has no effect in Mixed Lymphocyte Culture.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Constituent: 100% PBS
Sterile-filtered through 0.22 µm. Carrier and preservative free -
无载体
是 -
Concentration information loading... -
纯度
Ion Exchange Chromatography -
Primary antibody说明
This antibody has no effect in Mixed Lymphocyte Culture. -
克隆
单克隆 -
克隆编号
B-G3 -
骨髓瘤
x63-Ag8.653 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab27308于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Receptor for interleukin-2. -
疾病相关
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. -
序列相似性
Contains 2 Sushi (CCP/SCR) domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3559 Human
- Omim: 147730 Human
- SwissProt: P01589 Human
- Unigene: 231367 Human
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别名
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
see all
图片
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Flow Cytometry - Anti-IL-2 Receptor alpha antibody [B-G3] (ab27308)A typical staining pattern with ab27308 of PHA activated lymphocytes
数据表及文件
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Datasheet download
文献 (1)
ab27308 被引用在 1 文献中.
- Engert A et al. Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice. Int J Cancer 49:450-6 (1991). PubMed: 1917143
