Anti-IL-2抗体[JES6-1A12] (ab11510)
Key features and details
- Rat monoclonal [JES6-1A12] to IL-2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2a
概述
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产品名称
Anti-IL-2抗体[JES6-1A12]
参阅全部 IL-2 一抗 -
描述
大鼠单克隆抗体[JES6-1A12] to IL-2 -
宿主
Rat -
特异性
ab11510 recognises natural and recombinant mouse IL2. We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse IL-2.
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常规说明
Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified IgG prepared by affinity chromatography. -
克隆
单克隆 -
克隆编号
JES6-1A12 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab11510于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 20.28 kDa.
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说明 |
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WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 20.28 kDa. |
靶标
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功能
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
疾病相关
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
序列相似性
Belongs to the IL-2 family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 16183 Mouse
- SwissProt: P04351 Mouse
- Unigene: 14190 Mouse
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别名
- Aldesleukin antibody
- IL 2 antibody
- IL-2 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab11510 被引用在 2 文献中.
- Li X et al. Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice. Front Immunol 14:1185921 (2023). PubMed: 37228612
- Huang Y et al. The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice. Reprod Biol Endocrinol 19:14 (2021). PubMed: 33494759