Anti-IL-1F10抗体- C-terminal (ab180898)
Key features and details
- Rabbit polyclonal to IL-1F10 - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-IL-1F10抗体- C-terminal -
描述
兔多克隆抗体to IL-1F10 - C-terminal -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human IL-1F10 (C terminal). Peptide corresponds to 17 amino acids. NP_775184
Database link: Q8WWZ1 -
阳性对照
- Human liver tissue lysate and Human spleen tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180898于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 5 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 17 kDa).
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说明 |
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IHC-P
Use a concentration of 5 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 17 kDa). |
靶标
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功能
Binds soluble IL-1 receptor type 1. -
组织特异性
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. -
序列相似性
Belongs to the IL-1 family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 84639 Human
- Entrez Gene: 215274 Mouse
- Entrez Gene: 362077 Rat
- Omim: 615296 Human
- SwissProt: Q8WWZ1 Human
- SwissProt: Q8R459 Mouse
- Unigene: 306974 Human
- Unigene: 218750 Mouse
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别名
- family of interleukin 1-theta antibody
- FIL1 theta antibody
- FIL1T antibody
see all
图片
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All lanes : Anti-IL-1F10 antibody - C-terminal (ab180898) at 1 µg
Lane 1 : Human liver tissue lysate with Absent
Lane 2 : Human liver tissue lysate with Present
Lysates/proteins at 15 µg per lane.
Predicted band size: 17 kDa
Observed band size: 20 kDa why is the actual band size different from the predicted? -
Immunohistochemical analysis of paraffin-embedded Human spleen tissue, labeling IL1F10 using ab180898 at 5 μg/mL.
数据表及文件
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Datasheet download
文献 (4)
ab180898 被引用在 4 文献中.
- Zhou H et al. Interleukin-38 promotes skin tumorigenesis in an IL-1Rrp2-dependent manner. EMBO Rep 23:e53791 (2022). PubMed: 35578812
- The E et al. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proc Natl Acad Sci U S A 119:e2202577119 (2022). PubMed: 36037361
- Wei Y et al. Interleukin-38 alleviates cardiac remodelling after myocardial infarction. J Cell Mol Med 24:371-384 (2020). PubMed: 31746138
- Chen F et al. Interleukin-38 in colorectal cancer: a potential role in precision medicine. Cancer Immunol Immunother 69:69-79 (2020). PubMed: 31786620