Anti-IL-13 receptor alpha 1抗体(ab108499)
Key features and details
- Rabbit polyclonal to IL-13 receptor alpha 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IL-13 receptor alpha 1抗体
参阅全部 IL-13 receptor alpha 1 一抗 -
描述
兔多克隆抗体to IL-13 receptor alpha 1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment corresponding to Human IL-13 receptor alpha 1 aa 70-304.
Database link: BC015768 -
阳性对照
- A549 cell lysate. Human fetal heart tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in 200ul sterile H2O. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab108499于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 49 kDa.
|
| IHC-P |
1/100 - 1/500.
|
| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 49 kDa. |
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IHC-P
1/100 - 1/500. |
靶标
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功能
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. -
组织特异性
Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. -
序列相似性
Belongs to the type I cytokine receptor family. Type 5 subfamily. -
结构域
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3597 Human
- Entrez Gene: 16164 Mouse
- Entrez Gene: 252963 Rat
- Omim: 300119 Human
- SwissProt: P78552 Human
- SwissProt: O09030 Mouse
- Unigene: 496646 Human
- Unigene: 24208 Mouse
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别名
- bB128O4.2.1 (interleukin 13 receptor, alpha 1) antibody
- Cancer/testis antigen 19 antibody
- CD213a1 antibody
see all
图片
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Western blot - Anti-IL-13 receptor alpha 1 antibody (ab108499)Anti-IL-13 receptor alpha 1 antibody (ab108499) at 1/500 dilution + A549 cell lysate
Predicted band size: 49 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-13 receptor alpha 1 antibody (ab108499)1/100 ab108499 staining IL13 receptor alpha 1 in formalin-fixed, paraffin-embedded Human fetal heart tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab108499 被引用在 3 文献中.
- Huang L et al. Effect of platelet concentrate prepared by different methods on the healing of full-thickness skin defects. J Cosmet Dermatol 21:5910-5921 (2022). PubMed: 35778915
- Dutta AK et al. Signaling through the interleukin-4 and interleukin-13 receptor complexes regulates cholangiocyte TMEM16A expression and biliary secretion. Am J Physiol Gastrointest Liver Physiol 318:G763-G771 (2020). PubMed: 32090602
- Wang X et al. Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing. Front Bioeng Biotechnol 7:360 (2019). PubMed: 31921796