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AB244612

重组Anti-IL-1 beta抗体[EPR16805-15] - BSA and Azide free (Capture)

Anti-IL-1 beta antibody [EPR16805-15] - BSA and Azide free (Capture)

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(2 Publications)

Rabbit Recombinant Monoclonal IL-1 beta antibody. Carrier free. Suitable for sELISA and reacts with Rat samples. Cited in 2 publications.

查看别名

Interleukin-1 beta, IL-1 beta, Il1b

1 Images
Sandwich ELISA - Anti-IL-1 beta antibody [EPR16805-15] - BSA and Azide free (Capture) (AB244612)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-IL-1 beta antibody [EPR16805-15] - BSA and Azide free (Capture) (AB244612)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab255730).

不同偶联物与剂型 (2)

  • Unconjugated

    Anti-IL-1 beta antibody [EPR16805-15]

  • Carrier free

    Anti-IL-1 beta antibody [EPR16805-15] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR16805-15

亚型

IgG

不含载体蛋白

Yes

反应种属

Rat

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }

产品详情

ab244612 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Rat IL-1 beta. The recommended pair for sandwich ELISA is:
Capture: ab244612, Rat IL-1 beta Capture Antibody (unconjugated)
Detector: ab244864, Rat IL-1 beta Detector Antibody (unconjugated)
The reference range value is 54.69 - 3500 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis : its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
See full target information Il1b

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Evidence-based complementary and alternative medicine : eCAM 2021:5518750 PubMed34745289

2021

Unveiling the Mechanism of Principal Drugs of Lianpu Drink on Chronic Gastritis by Network Pharmacology.

Applications

Unspecified application

Species

Unspecified reactive species

Shuhan Zhou,Xiaohui Xu,Jiangqin Zeng,Zhiyi Liu,Miao Wang,Wenliang Lv

Immunity 13:233-42 PubMed10981966

2000

Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function.

Applications

Unspecified application

Species

Unspecified reactive species

G J Wright,M J Puklavec,A C Willis,R M Hoek,J D Sedgwick,M H Brown,A N Barclay
View all publications

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