Anti-IgE抗体[4C3] (ab106494)
![Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)](https://www.abcam.cn/ps/products/106/ab106494/Images/ab106494-118874-anti-ige-antibody-4c3-sandwich-elisa.jpg "Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)")
Key features and details
- Mouse monoclonal [4C3] to IgE
- Suitable for: Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-IgE抗体[4C3]
参阅全部 IgE 一抗 -
描述
小鼠单克隆抗体[4C3] to IgE -
宿主
Mouse -
特异性
ab106494 is specific for Human IgE. It reacts with IgE purified from blood but does not cross-react with Human anti-IgG1, IgG2, IgG3, IgG4, IgA and IgM
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经测试应用
适用于: Sandwich ELISAmore details -
种属反应性
与反应: Human
不与反应: Mouse -
免疫原
Recombinant full length protein corresponding to Human IgE aa 1-550.
Database link: P01854 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
4C3 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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ELISA pair antibody
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106494于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Sandwich ELISA |
Use a concentration of 5 µg/ml.
for coating plates. Use ab106493 for detection. |
| 说明 |
|---|
|
Sandwich ELISA
Use a concentration of 5 µg/ml. for coating plates. Use ab106493 for detection. |
靶标
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相关性
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock. -
细胞定位
Cell Membrane -
数据库链接
- Entrez Gene: 3497 Human
- Omim: 147180 Human
- SwissProt: P01854 Human
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别名
- Igh2 antibody
- IGHE antibody
- IGHEP1 antibody
- Immunoglobulin heavy constant epsilon antibody
图片
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Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)ab106494 used at 5 µg/ml for coating ELISA plates to capture Human IgE. Detection utilised ab106493 at 1/1000 dilution.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab106494 被引用在 2 文献中.
- Zhang Y et al. An allergenic plant calmodulin from Artemisia pollen primes human DCs leads to Th2 polarization. Front Immunol 13:996427 (2022). PubMed: 36248805
- Leung S et al. Multiplexed immunoassay approach to characterize antidrug antibody like specific reactivity. Bioanalysis 11:703-712 (2019). PubMed: 30994012