抗人IgM抗体(ab26867)
Key features and details
- Chicken polyclonal to Human IgM
- Suitable for: WB
- Reacts with: Human
- Isotype: IgY
概述
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产品名称
抗人IgM抗体
参阅全部 Human IgM 一抗 -
描述
鸡多克隆抗体to人IgM -
宿主
Chicken -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Full length native protein (purified) (Human): IgM from plasma.
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阳性对照
- Human plasma protein
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Protein L purified -
纯化说明
ab26867 is an affinity purified IgY. -
克隆
多克隆 -
同种型
IgY -
研究领域
相关产品
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab26867于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa).
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说明 |
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WB
1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa). |
靶标
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相关性
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. -
细胞定位
Cell Membrane and Secreted -
数据库链接
- Entrez Gene: 3507 Human
- Omim: 147020 Human
- SwissProt: P01871 Human
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别名
- Immunoglobin heavy chain constant region mu antibody
- AGM1 antibody
- Constant region of heavy chain of IgM antibody
see all
图片
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Anti-Human IgM antibody (ab26867) at 1/500 dilution + Human plasma protein
Secondary
HRP conjugated goat anti-IgY at 1/1000 dilution
Predicted band size: 75 kDa
Observed band size: 25,75 kDa why is the actual band size different from the predicted?
Colorimetric method for signal development
数据表及文件
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Datasheet download
文献 (0)
ab26867 尚未被引用在任何文献中。