抗人IgG抗体[I17-T] (ab180635)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Human IgG antibody [I17-T] (ab180635)](https://www.abcam.cn/ps/products/180/ab180635/Images/ab180635-209477-anti-human-igg-antibody-i17-t-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Human IgG antibody [I17-T] (ab180635)")
Key features and details
- Rabbit monoclonal [I17-T] to Human IgG
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
抗人IgG抗体[I17-T]
参阅全部 Human IgG 一抗 -
描述
兔单克隆抗体[I17-T] to人IgG -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human Human IgG (C terminal). The exact sequence is proprietary. Additional Protein accession number: P01857, P01859, P01860, P01861
Database link: P01857 -
表位
Antibody recognizes the epitope located between Ala261 - Lys275 -
阳性对照
- IgG positive plasma cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.32% Tris HCl, 2% BSA -
Concentration information loading... -
纯度
Proprietary Purification -
纯化说明
This immunoglobulin is the product of one single B-cell line from the crude anti-peptide polyclonal anti-serum. This antibody is purified using a propriety technique and offers a completely post-translationally modified and properly glycosylated antibody. This offers increased stability. -
克隆
单克隆 -
克隆编号
I17-T -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab180635于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100 - 1/300. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
1/100 - 1/300. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. |
靶标
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相关性
IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). -
细胞定位
Cell Membrane and Secreted -
数据库链接
- Entrez Gene: 3500 Human
- Entrez Gene: 3501 Human
- Entrez Gene: 3502 Human
- Entrez Gene: 3503 Human
- Omim: 147100 Human
- Omim: 147110 Human
- Omim: 147120 Human
- Omim: 147130 Human
see all -
别名
- FLJ39988 antibody
- FLJ40036 antibody
- FLJ40253 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Human IgG antibody [I17-T] (ab180635)
Immunohistochemical analysis of paraffin-embedded IgG positive Human plasma cells, in the case of IgG4-related chronic sclerosing sialoadenitis, using ab180635 at a 1/100 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.
数据表及文件
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Datasheet download
文献 (0)
ab180635 尚未被引用在任何文献中。
