Anti-HSV1 ICP0抗体[5H7] (ab6513)
![Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)](https://www.abcam.cn/ps/products/6/ab6513/Images/ab6513-12352-anti-hsv1-icp0-antibody-5h7-immunofluorescence.jpg "Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)")
Key features and details
- Mouse monoclonal [5H7] to HSV1 ICP0
- Suitable for: WB, ELISA, ICC/IF
- Reacts with: Herpes simplex virus
- Isotype: IgG1
概述
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产品名称
Anti-HSV1 ICP0抗体[5H7] -
描述
小鼠单克隆抗体[5H7] to HSV1 ICP0 -
宿主
Mouse -
经测试应用
适用于: WB, ELISA, ICC/IFmore details -
种属反应性
与反应: Herpes simplex virus -
免疫原
Herpes Virus
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4 -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
5H7 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/8000.
|
|
| ELISA |
1/12800.
|
|
| ICC/IF | (1) |
1/25600.
|
| 说明 |
|---|
|
WB
1/8000. |
|
ELISA
1/12800. |
|
ICC/IF
1/25600. |
靶标
-
相关性
Herpes simplex virus (HSV) encodes four nuclear phosphoproteins that contribute towards the full productive lytic cycle cascade in newly infected permissive cells. The IE175 (or ICP4) and IE63 (or ICP27) proteins have essential regulatory roles during the lytic cycle. A third, IE110 (or ICP0), appears to play only an accessory role in the presence of VP16, but in the absence of VP16 appears to be critical for initiation of reactivated infections. -
细胞定位
Nuclear -
数据库链接
- SwissProt: P08393 Herpes simplex virus
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别名
- Alpha 0 protein antibody
- Herpes siplex virus 1 antibody
- HHV1 ICP0 antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)This image is courtesy of an anonymous Abreviewab6513 (1/25600) staining HSV1 ICP0 in human cells. Cells were PFA-fixed, permeabilized in 0.3% TritonX-100/PBS and blocked in 1% serum /30 minutes /25oC. A fluorescently labeled donkey anti-mouse antibody was used as the secondary.
实验方案
数据表及文件
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Datasheet download
文献 (39)
ab6513 被引用在 39 文献中.
- Malikov V et al. FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression. Cell Rep 38:110396 (2022). PubMed: 35172151
- Jbara-Agbaria D et al. Liposomal siRNA Formulations for the Treatment of Herpes Simplex Virus-1: In Vitro Characterization of Physicochemical Properties and Activity, and In Vivo Biodistribution and Toxicity Studies. Pharmaceutics 14:N/A (2022). PubMed: 35336008
- Wang Z et al. Oleanolic Acid Derivative AXX-18 Exerts Antiviral Activity by Inhibiting the Expression of HSV-1 Viral Genes UL8 and UL52. Viruses 14:N/A (2022). PubMed: 35746758
- Shan T et al. Viral UL8 Is Involved in the Antiviral Activity of Oleanolic Acid Against HSV-1 Infection. Front Microbiol 12:689607 (2021). PubMed: 34354687
- Suryawanshi RK et al. mTORC2 confers neuroprotection and potentiates immunity during virus infection. Nat Commun 12:6020 (2021). PubMed: 34650053
