Anti-HSV1 + HSV2 ICP5 Major Capsid蛋白抗体[3B6] - BSA and Azide free (ab6508)
![Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 ICP5 Major Capsid Protein antibody [3B6] - BSA and Azide free (ab6508)](https://www.abcam.cn/ps/products/6/ab6508/Images/ab6508-12349-anti-hsv1-hsv2-icp5-major-capsid-protein-antibody-3b6-immunofluorescence.jpg "Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 ICP5 Major Capsid Protein antibody [3B6] - BSA and Azide free (ab6508)")
Key features and details
- Mouse monoclonal [3B6] to HSV1 + HSV2 ICP5 Major Capsid Protein - BSA and Azide free
- Suitable for: IHC-P, WB, ELISA, ICC/IF
- Reacts with: Herpes simplex virus, Human herpesvirus 2
- Isotype: IgG2b
概述
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产品名称
Anti-HSV1 + HSV2 ICP5 Major Capsid蛋白抗体[3B6] - BSA and Azide free -
描述
小鼠单克隆抗体[3B6] to HSV1 + HSV2 ICP5 Major Capsid蛋白- BSA and Azide free -
宿主
Mouse -
经测试应用
适用于: IHC-P, WB, ELISA, ICC/IFmore details -
种属反应性
与反应: Herpes simplex virus, Human herpesvirus 2 -
免疫原
Tissue, cells or virus corresponding to HSV1 + HSV2 ICP5 Major Capsid Protein.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: PBS -
无载体
是 -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
3B6 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (1) |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
Western Blot Titer: HSV-1 >1:3,200; HSV-2 >1:3,200. |
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| ELISA |
Use at an assay dependent concentration.
ELISA titer: HSV-1 0.100 @ >1:102,400; HSV-2 0.100 @ >1:102,400. |
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| ICC/IF |
1/200. PubMed: 18701599
IFA titer: HSV-1 1+ @ 1:3,200; HSV-2 1+ @ 1:3,200. |
| 说明 |
|---|
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IHC-P
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. Western Blot Titer: HSV-1 >1:3,200; HSV-2 >1:3,200. |
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ELISA
Use at an assay dependent concentration. ELISA titer: HSV-1 0.100 @ >1:102,400; HSV-2 0.100 @ >1:102,400. |
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ICC/IF
1/200. PubMed: 18701599 IFA titer: HSV-1 1+ @ 1:3,200; HSV-2 1+ @ 1:3,200. |
靶标
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相关性
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of the herpes virus family, Herpesviridae, which cause infections in humans. They are also called Human Herpes Virus 1 and 2 (HHV-1 and HHV-2) and are neurotropic and neuroinvasive viruses; they enter and hide in the human nervous system, accounting for their durability in the human body. -
数据库链接
- Entrez Gene: 1487302 Herpes simplex virus
- Entrez Gene: 2703368 Herpes simplex virus
- SwissProt: P06491 Herpes simplex virus
- SwissProt: P89442 Herpes simplex virus
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别名
- Capsid protein VP5 antibody
- Herpes simplex virus 1 major capsid protein antibody
- Herpes simplex virus 2 major capsid protein antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 ICP5 Major Capsid Protein antibody [3B6] - BSA and Azide free (ab6508)Image from Ohta A et al., Virol J. 2011 Jul 26;8:365. doi: 10.1186/1743-422X-8-365.; Fig 4.; 26 July 2011, Virology Journal 2011, 8:365Immunofluorescence analysis of HSV infected cells, 7 hours (left) or 17 hours (right) post-infection, staining HSV1 + HSV2 ICP5 Major Capsid Protein with ab6508 at 1/200 dilution.
Cells were fixed for 10 min in paraformaldehyde, permeabilized in 0.1% Triton X-100 and blocked in 4% goat serum, 1% bovine serum albumin, before incubating with primary antibody for 30 min at room temperature. An AlexaFluor®647-conjugated goat anti-mouse IgG1 was used as the secondary antibody.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (43)
ab6508 被引用在 43 文献中.
- Duncan CJA et al. Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic. J Exp Med 219:N/A (2022). PubMed: 35442417
- Chaturvedi S et al. Disrupting autorepression circuitry generates "open-loop lethality" to yield escape-resistant antiviral agents. Cell 185:2086-2102.e22 (2022). PubMed: 35561685
- Wang Y et al. Single-cell RNA-sequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport. Int J Biol Sci 16:1586-1603 (2020). PubMed: 32226304
- Chen Y et al. Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion Neurons. Mol Ther Methods Clin Dev 18:33-43 (2020). PubMed: 32577430
- Wang W et al. Guanidine modifications enhance the anti-herpes simplex virus activity of (E,E)-4,6-bis(styryl)-pyrimidine derivatives in vitro and in vivo. Br J Pharmacol 177:1568-1588 (2020). PubMed: 31709511