Anti-HSD17B4抗体[8E5AB11] (ab110297)
![Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)](https://www.abcam.cn/ps/products/110/ab110297/Images/ab110297-123538-anti-hsd17b4-antibody-8e5ab11-immunoprecipitation.jpg "Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)")
Key features and details
- Mouse monoclonal [8E5AB11] to HSD17B4
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG3
概述
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产品名称
Anti-HSD17B4抗体[8E5AB11]
参阅全部 HSD17B4 一抗 -
描述
小鼠单克隆抗体[8E5AB11] to HSD17B4 -
宿主
Mouse -
经测试应用
适用于: IPmore details -
种属反应性
与反应: Human -
免疫原
The details of the immunogen for this antibody are not available.
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阳性对照
- Human Liver Microsomes.
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常规说明
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Product was previously marketed under the MitoSciences sub-brand.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
存储溶液
pH: 7.5
Preservative: 0.02% Sodium azide
Constituent: HEPES buffered saline -
Concentration information loading... -
纯度
Ammonium Sulphate Precipitation -
纯化说明
ab110297 is produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation. -
克隆
单克隆 -
克隆编号
8E5AB11 -
同种型
IgG3 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110297于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP |
Use at an assay dependent dilution.
|
| 说明 |
|---|
|
IP
Use at an assay dependent dilution. |
靶标
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功能
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. -
组织特异性
Present in many tissues with highest concentrations in liver, heart, prostate and testis. -
通路
Lipid metabolism; fatty acid beta-oxidation. -
疾病相关
D-bifunctional protein deficiency
Perrault syndrome 1 -
序列相似性
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Contains 1 MaoC-like domain.
Contains 1 SCP2 domain. -
细胞定位
Peroxisome. - Information by UniProt
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数据库链接
- Entrez Gene: 3295 Human
- Omim: 601860 Human
- SwissProt: P51659 Human
- Unigene: 406861 Human
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别名
- 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase antibody
- 17 beta HSD 4 antibody
- 17 beta HSD IV antibody
see all
图片
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Immunoprecipitation - Anti-HSD17B4 antibody [8E5AB11] (ab110297)Immunoprecipitation with ab110297 from Human Liver Microsomes.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab110297 被引用在 1 文献中.
- Jo DS et al. Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. Autophagy 16:1989-2003 (2020). PubMed: 31964216