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AB20944

HRP Anti-Rubella Virions抗体

HRP Anti-Rubella Virions antibody

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Goat Polyclonal Rubella Virions antibody - conjugated to HRP. Suitable for ICC and reacts with Rubella virus samples.

关键信息

宿主种属

Goat

克隆

Polyclonal

亚型

IgG

偶联物

HRP

激发波长/发射波长
不含载体蛋白

No

反应种属

Rubella virus

应用

ICC

applications

特异性

Purified virions. Negative against Vero cells by indirect immunofluorescence.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rubella virus": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>" } } }

产品详情

Covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed. Estimated molar HRP:IgG substitution is 2-3. Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
存储溶液
Preservative: 0.002% Thimerosal (merthiolate) Constituents: PBS, 1% BSA
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Rubella virions also known as rubella virus particles are spherical and enveloped entities with an average diameter of 50-70 nm. These virions are composed mainly of three structural proteins: the capsid protein and the envelope glycoproteins E1 and E2. Within the host cell rubella virions replicate in the cytoplasm of infected epithelial cells. Their envelope derives from the host cell membrane highlighting their interaction with the infected host during budding.
Biological function summary

Rubella virions serve as the infectious agents responsible for the transmission of rubella which is a contagious disease characterized by rash and fever. As individual units rubella virions do not form part of a complex with other viruses but require assembly via interactions among the capsid protein and envelope glycoproteins. The virion structure plays a central role in facilitating host cell receptor binding and membrane fusion which allows the virus to deliver its RNA genome into host cells for replication.

Pathways

Viral entry and replication mechanisms drive the activities of rubella virions. The virions exploit the endocytic pathway to enter host cells a process that is important for initiating infection. During replication non-structural proteins facilitate the synthesis of viral components. Important proteins in these processes include the E1 glycoprotein which is involved in receptor interaction and membrane fusion an integral part of the virion's infection cycle.

Rubella virions are primarily linked to rubella infection also known as German measles and congenital rubella syndrome. This viral infection triggers an immune response in the host involving cytokines and antibodies notably the anti-rubella antibody which helps clear the virus. Congenital rubella syndrome occurs when maternal infection during pregnancy results in significant developmental anomalies in the fetus. This association highlights the importance of monitoring and vaccination efforts to prevent these serious conditions.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

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