AB194981

重组HRP Anti-CD41抗体[EPR4330]

HRP Anti-CD41 antibody [EPR4330]

RabMAb
Recombinant
了解详情

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(2 Publications)

Rabbit Recombinant Monoclonal CD41 antibody - conjugated to HRP. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Cited in 2 publications.

查看别名

CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb

1 Images

Lab

Western blot - HRP Anti-CD41 antibody [EPR4330] (AB194981)

This blot was produced using a 4-12% Bis-tris gel under the MOPS buffer system. The gel was run at 200V for 50 minutes before being transferred onto a Nitrocellulose membrane at 30V for 70 minutes. The membrane was then blocked for an hour using 3% milk before being incubated with ab194981 overnight at 4°C. Antibody binding was visualised using ECL development solution ab133406.

All lanes:

Western blot - HRP Anti-CD41 antibody [EPR4330] (ab194981) at 1/5000 dilution

All lanes:

Platelet (Human) Whole Cell Lysate at 10 µg

Predicted band size: 113 kDa

Observed band size: 113 kDa

true

Exposure time: 20min

不同偶联物与剂型 (8)

665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-CD41 antibody [EPR4330]
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-CD41 antibody [EPR4330]
603 Alexa Fluor® 568

Alexa Fluor® 568 Anti-CD41 antibody [EPR4330]
565 Alexa Fluor® 555

Alexa Fluor® 555 Anti-CD41 antibody [EPR4330]
775 Alexa Fluor® 750

Alexa Fluor® 750 Anti-CD41 antibody [EPR4330]
Unconjugated

Anti-CD41 antibody [EPR4330]
Carrier free

Anti-CD41 antibody [EPR4330] - BSA and Azide free
Carrier free

Anti-CD41 antibody [EPR4330] - Low endotoxin, Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR4330

亚型

IgG

偶联物

HRP

激发波长/发射波长

不含载体蛋白

反应种属

Human, Human, Mouse

应用

IHC-P, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/5000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.4 Preservative: 0.1% Proclin 300 Solution Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle|Store in the dark

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Integrin alpha-IIb/beta-3 (ITGA2B : ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). Integrin ITGA2B : ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets (PubMed : 12477717).

See full target information ITGA2B

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 72:517-544 PubMed39215640

2024

Making Multiplexed Imaging Flexible: Combining Essential Markers With Established Antibody Panels.

Applications

Unspecified application

Species

Unspecified reactive species

Ashik Jawahar Deen,Johan Thorsson,Eleanor M O'Roberts,Pranauti Panshikar,Tony Ullman,David Krantz,Carolina Oses,Charlotte Stadler

Pharmaceuticals (Basel, Switzerland) 14: PubMed34451836

2021

GMP-Compliant Radiosynthesis of [F]GP1, a Novel PET Tracer for the Detection of Thrombi.

Applications

Unspecified application

Species

Unspecified reactive species

Verena Hugenberg,Marion Zerna,Mathias Berndt,Reinhard Zabel,Rainer Preuss,Dirk Rolfsmeier,Janet Wegener,Henrik Fox,Astrid Kassner,Hendrik Milting,Norman Koglin,Andrew W Stephens,Jan F Gummert,Wolfgang Burchert,Marcus-André Deutsch

View all publications

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