Anti-HPV18 E6抗体[BF7] (ab20192)
Key features and details
- Mouse monoclonal [BF7] to HPV18 E6
- Suitable for: WB, RIA, ELISA
- Reacts with: Human papillomavirus type 18
- Isotype: IgG1
概述
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产品名称
Anti-HPV18 E6抗体[BF7] -
描述
小鼠单克隆抗体[BF7] to HPV18 E6 -
宿主
Mouse -
经测试应用
适用于: WB, RIA, ELISAmore details -
种属反应性
与反应: Human papillomavirus type 18 -
免疫原
Fusion protein corresponding to Human papillomavirus HPV18 E6.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading... -
纯度
Protein A/G purified -
克隆
单克隆 -
克隆编号
BF7 -
骨髓瘤
NS1 -
同种型
IgG1 -
轻链类型
unknown -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab20192于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use at an assay dependent dilution. Predicted molecular weight: 17 kDa.
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| RIA |
Use at an assay dependent dilution.
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| ELISA |
Use at an assay dependent dilution.
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| 说明 |
|---|
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WB
Use at an assay dependent dilution. Predicted molecular weight: 17 kDa. |
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RIA
Use at an assay dependent dilution. |
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ELISA
Use at an assay dependent dilution. |
靶标
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相关性
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. -
别名
- E6 antibody
- Human papillomavirus type 18 E6 antibody
- Protein E6 antibody
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab20192 被引用在 3 文献中.
- Yin S et al. MicroRNA-130a regulated by HPV18 E6 promotes proliferation and invasion of cervical cancer cells by targeting TIMP2. Exp Ther Med 17:2837-2846 (2019). PubMed: 30906471
- Cheng Y et al. Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2. Mol Med Rep 16:5464-5470 (2017). PubMed: 28849054
- Banks L et al. Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas. J Gen Virol 68 ( Pt 5):1351-9 (1987). PubMed: 3033140