Anti-HPV16 E1+E4抗体[TVG 403] (ab20190)
Key features and details
- Mouse monoclonal [TVG 403] to HPV16 E1+E4
- Suitable for: IHC-Fr, ELISA, Flow Cyt
- Reacts with: Human papillomavirus type 16
- Isotype: IgG1
概述
-
产品名称
Anti-HPV16 E1+E4抗体[TVG 403]
参阅全部 HPV16 E1+E4 一抗 -
描述
小鼠单克隆抗体[TVG 403] to HPV16 E1+E4 -
宿主
Mouse -
经测试应用
适用于: IHC-Fr, ELISA, Flow Cytmore details -
种属反应性
与反应: Human papillomavirus type 16 -
免疫原
Fusion protein (Human). Antigen for hybridoma production was expressed as a b-galactosidase fusion protein using the pEX expression system and was consequently cleaved to release the E1/E4 polypeptide.
-
表位
E1/E4 protein is aa 36-41 of human papilloma virus type 16. -
常规说明
This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading... -
纯度
Protein A/G purified -
Primary antibody说明
This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer. -
克隆
单克隆 -
克隆编号
TVG 403 -
骨髓瘤
NS0 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab20190于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr |
Use at an assay dependent concentration.
|
|
| ELISA |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 说明 |
|---|
|
IHC-Fr
Use at an assay dependent concentration. |
|
ELISA
Use at an assay dependent concentration. |
|
Flow Cyt
Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
-
相关性
HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans. -
细胞定位
Nuclear -
别名
- ATP dependent helicase E1 antibody
- E1 antibody
- E4 antibody
see all
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab20190 被引用在 1 文献中.
- Doorbar J et al. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J Virol 74:10081-95 (2000). PubMed: 11024137