Anti-HoxC6抗体(ab41587)
Key features and details
- Rabbit polyclonal to HoxC6
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-HoxC6抗体
参阅全部 HoxC6 一抗 -
描述
兔多克隆抗体to HoxC6该产品是 快线抗体，通过亲和纯化得到。对抗原肽有高灵敏度及特异性（ELISA测试）。 Read the terms of use »
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宿主
Rabbit -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human HoxC6 aa 100-200 conjugated to keyhole limpet haemocyanin.
(Peptide available asab41586) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (1) |
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody.
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| WB |
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa.
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| 说明 |
|---|
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IHC-P
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody. |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa. |
靶标
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功能
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
序列相似性
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 3223 Human
- Entrez Gene: 15425 Mouse
- Entrez Gene: 252885 Rat
- Omim: 142972 Human
- SwissProt: P09630 Human
- SwissProt: P10629 Mouse
- Unigene: 549040 Human
- Unigene: 4444 Mouse
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别名
- CP25 antibody
- HHO.C8 antibody
- Homeo box 3C antibody
see all
图片
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Western blot - Anti-HoxC6 antibody (ab41587)All lanes : Anti-HoxC6 antibody (ab41587)
Lane 1 : Human ovary tissue lysate
Lane 2 : Human ovary tumor tissue lysate
Lane 3 : SK-N-BE cell lysate
Lane 4 : PC3 cell lysate
Lane 5 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Exposure time: 8 minutes
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (11)
ab41587 被引用在 11 文献中.
- Wang Q et al. Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development. Burns Trauma 10:tkac013 (2022). PubMed: 35547861
- Qi ZP et al. HDAC2 promotes the EMT of colorectal cancer cells and via the modular scaffold function of ENSG00000274093.1. J Cell Mol Med 25:1190-1197 (2021). PubMed: 33325150
- Qi L et al. HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/ß-catenin axis in right-sided colon cancer. Cell Death Dis 12:337 (2021). PubMed: 33795652
- Yang P et al. Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma. Cancer Manag Res 11:8167-8179 (2019). PubMed: 31564976
- Zhang F et al. HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-ß/smad signaling pathway in cervical carcinoma cells. Cancer Cell Int 18:204 (2018). PubMed: 30559605