Anti-HOPX/HOD抗体(ab226807)
Key features and details
- Rabbit polyclonal to HOPX/HOD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-HOPX/HOD抗体
参阅全部 HOPX/HOD 一抗 -
描述
兔多克隆抗体to HOPX/HOD -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Pig
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免疫原
Recombinant fragment within Human HOPX/HOD (internal sequence). The exact sequence is proprietary.
Database link: Q9BPY8 -
阳性对照
- WB: Human brain tissue extracts.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab226807于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 8 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 8 kDa. |
靶标
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功能
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. -
组织特异性
Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. -
序列相似性
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 281270 Cow
- Entrez Gene: 84525 Human
- Entrez Gene: 74318 Mouse
- Entrez Gene: 396692 Pig
- Entrez Gene: 171160 Rat
- Omim: 607275 Human
- SwissProt: Q8MJD5 Cow
- SwissProt: Q9BPY8 Human
see all -
形式
There are 2 isoforms produced by alternative splicing. -
别名
- CAMEO antibody
- heart odd homeobox 1 protein antibody
- HOD antibody
see all
图片
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Western blot - Anti-HOPX/HOD antibody (ab226807)Anti-HOPX/HOD antibody (ab226807) at 1/500 dilution + human brain tissue extract at 30 µg
Developed using the ECL technique.
Predicted band size: 8 kDa
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab226807 尚未被引用在任何文献中。