Anti-HOPX/HOD抗体(ab106251)
Key features and details
- Rabbit polyclonal to HOPX/HOD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-HOPX/HOD抗体
参阅全部 HOPX/HOD 一抗 -
描述
兔多克隆抗体to HOPX/HOD -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Pig
-
免疫原
Recombinant full length protein corresponding to Human HOPX/HOD aa 1-73. (BC014225)
Sequence:MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKW FKQRLAKWRRSEGLPSECRSVTD
-
阳性对照
- Human fetal heart tissue lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.184% Tris glycine, 1% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106251于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 8 kDa).
|
| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 8 kDa). |
靶标
-
功能
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. -
组织特异性
Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. -
序列相似性
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 281270 Cow
- Entrez Gene: 84525 Human
- Entrez Gene: 74318 Mouse
- Entrez Gene: 396692 Pig
- Entrez Gene: 171160 Rat
- Omim: 607275 Human
- SwissProt: Q8MJD5 Cow
- SwissProt: Q9BPY8 Human
see all -
形式
There are 2 isoforms produced by alternative splicing. -
别名
- CAMEO antibody
- heart odd homeobox 1 protein antibody
- HOD antibody
see all
图片
-
Western blot - Anti-HOPX/HOD antibody (ab106251)Anti-HOPX/HOD antibody (ab106251) at 1/500 dilution + Human fetal heart tissue lysate
Predicted band size: 8 kDa
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab106251 被引用在 1 文献中.
- Sengupta A et al. A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System. Front Toxicol 4:840606 (2022). PubMed: 35832493