Anti-HMW Cytokeratin抗体[34bE12] (ab776)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)](https://www.abcam.cn/ps/products/0/ab776/Images/ab776-3-anti-hmw-cytokeratin-antibody-immunohistochemistry-prostate-human.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)")
Key features and details
- Mouse monoclonal [34bE12] to HMW Cytokeratin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-HMW Cytokeratin抗体[34bE12] -
描述
小鼠单克隆抗体[34bE12] to HMW Cytokeratin -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human HMW Cytokeratin. Solubilized keratin extract from human stratum corneum.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.3
Preservative: 0.05% Sodium azide
Constituents: Tissue culture supernatant, 1% BSA -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
34bE12 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/25 - 1/50.
Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Enzymatic antigen retrieval of paraffin embedded tissues is recommended prior to immunostaining. |
| 说明 |
|---|
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IHC-P
1/25 - 1/50. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Enzymatic antigen retrieval of paraffin embedded tissues is recommended prior to immunostaining. |
靶标
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相关性
Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58), CK6 (56), CK7 (54), CK8 (52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16( 48), CK17 (46), CK18 (45), CK19(48) and CK20(46). -
细胞定位
Cytoplasmic -
数据库链接
- Entrez Gene: 3860 Human
- Entrez Gene: 3861 Human
- Entrez Gene: 3866 Human
- Entrez Gene: 3868 Human
- Omim: 148030 Human
- Omim: 148065 Human
- Omim: 148066 Human
- Omim: 148067 Human
see all -
别名
- CK13 antibody
- CK14 antibody
- CK15 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)Formalin fixed paraffin embedded human prostate tissue, staining HMW Cytokeratin with ab776 in immunohistochemical analysis
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)](https://www.abcam.cn/ps/products/0/ab776/Images/ab776-3705-anti-hmw-cytokeratin-antibody-34be12-immunohistochemistry.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)ab776 staining human skin tissue sections by IHC-P.
数据表及文件
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Datasheet download
文献 (2)
ab776 被引用在 2 文献中.
- Hermanova I et al. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer. J Exp Med 217:N/A (2020). PubMed: 32219437
- Hagman Z et al. miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br J Cancer 108:1668-76 (2013). IHC ; Human . PubMed: 23571738
