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Anti-HLA-DQ抗体[TAL 4.1] (ab20173)

Submit a review Q&A (2)References (3)

Key features and details

  • Mouse monoclonal [TAL 4.1] to HLA-DQ
  • Suitable for: WB, ELISA, IHC-Fr, Flow Cyt
  • Reacts with: Human
  • Isotype: IgG2b

概述

  • 产品名称

    Anti-HLA-DQ抗体[TAL 4.1]
    参阅全部 HLA-DQ 一抗

  • 描述

    小鼠单克隆抗体[TAL 4.1] to HLA-DQ

  • 宿主

    Mouse

  • 经测试应用

    适用于: WB, ELISA, IHC-Fr, Flow Cytmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    Tissue, cells or virus corresponding to Human HLA-DQ.

  • 常规说明

    Recommended growth conditions: RPMI1640 + 10%FCS

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 存储溶液

    Preservative: 0.02% Sodium azide
    Constituent: 99.98% PBS
  • Concentration information loading...

  • 纯度

    Protein A/G purified

  • 克隆

    单克隆

  • 克隆编号

    TAL 4.1

  • 骨髓瘤

    P3-NS1/1-Ag4-1

  • 同种型

    IgG2b

  • 轻链类型

    unknown

  • 研究领域

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab20173于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.
IHC-Fr
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration.

ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
说明
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.
IHC-Fr
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration.

ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

靶标

  • 相关性

    Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens: class I (HLA A, HLA B and HLA C) and class II (HLA D).

  • 细胞定位

    Type I membrane protein

  • 数据库链接

    • 别名

      • CD antibody
      • CELIAC1 antibody
      • DC 4 alpha chain antibody
      • DC alpha antibody
      • DQ A1 antibody
      • Gluten sensitive enteropathy (celiac disease) antibody
      • GSE antibody
      • HLA Class II DQ antibody
      • HLA class II histocompatibility antigen DQ antibody
      • HLA class II histocompatibility antigen DQ(1) alpha chain antibody
      • HLA class II histocompatibility antigen DQ(3) alpha chain antibody
      • HLA DCA antibody
      • HLA DQA antibody
      • HLA DQA1 antibody
      • HLA DQB antibody
      • HLA DQB1 antibody
      • HLA-DQA1 antibody
      • IDDM 1 antibody
      • IDDM1 antibody
      • Leucocyte antigen DQA1 antibody
      • Major histocompatibility complex class II DQ alpha 1 antibody
      • Major histocompatibility complex class II DQ beta 1 antibody
      • MHC class II antigen HLA DQ beta 1 antibody
      • MHC class II HLA DQ alpha 1 antibody
      • MHC class II HLA DQ beta glycoprotein antibody
      • MHC DQ beta antibody
      • MHC HLA DQ alpha antibody
      see all

    文献 (3)

    发表研究结果有使用 ab20173？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab20173 被引用在 3 文献中.

    • Goodlet KJ  et al. COVID-19 in a lung transplant recipient: Exploring the diagnostic role of circulating exosomes and the clinical impact of advanced immunosuppression. Transpl Infect Dis 23:e13480 (2021). PubMed: 32997881
    • Kanangat S  et al. Circulating histocompatibility antigen (HLA) gene products may help differentiate benign from malignant indeterminate pulmonary lesions. Hum Immunol 79:558-563 (2018). WB . PubMed: 29656111
    • Bodmer JG & Bodmer WF Monoclonal antibodies to HLA determinants. Br Med Bull 40:267-75 (1984). PubMed: 6205714

    客户评价及客户问答

    Show All 评价 Q&A
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    1-2 of 2 Abreviews or Q&A

    Question

    Do you know the epitope region of this product? The DQ protein contains a lot of diversity. Therefore, can you tell me which form of DQ that this product will detect?

    Read More
    Answer

    Thank you for your enquiry. I can confirm that this antibody detects HLA DQ1, DQ5 and DQ6. Also, the antibody western blots to dimer and DQ beta chain.Unfortunately, we do not know the epitope region. I hope this information will be helpful.

    Read More

    Question

    1) Was this product made using an immunogen peptide that is specific to HLA DQ? 2) What method did you used to determine the specificity?

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    Answer

    Thank you for your enquiry. I am afraid that we have no specific information here that will help. The best I can do is to suggest the following reference, which I hope will be helpful: Bodmer J et al. 1984. Histocompatibility Testing. 432-438 Sorry I am unable to help you on this occasion.

    Read More

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