Anti-HLA class I ABC抗体(ab126237)
Key features and details
- Rabbit polyclonal to HLA class I ABC
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-HLA class I ABC抗体 -
描述
兔多克隆抗体to HLA class I ABC -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to a region within amino acids 1 and 206 of Human HLA class I A, B, C (AAH03069).
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阳性对照
- A549 whole cell lysate; HepG2 whole cell lysate (ab7900)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab126237于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa. |
靶标
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功能
Involved in the presentation of foreign antigens to the immune system. -
序列相似性
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
翻译后修饰
Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3105 Human
- Entrez Gene: 3106 Human
- Entrez Gene: 3107 Human
- Omim: 142800 Human
- Omim: 142830 Human
- Omim: 142840 Human
- SwissProt: P01889 Human
- SwissProt: P04222 Human
see all -
别名
- 1A03_HUMAN antibody
- A-1 alpha chain antibody
- A-3 alpha chain antibody
see all
图片
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Western blot - Anti-HLA class I ABC antibody (ab126237)Anti-HLA class I ABC antibody (ab126237) at 1/1000 dilution + A549 whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab126237 被引用在 1 文献中.
- Khazan-Kost S et al. Soluble HLA peptidome of pleural effusions is a valuable source for tumor antigens. J Immunother Cancer 10:N/A (2022). PubMed: 35580925