Anti-HIV1 p24抗体(ab63913)
Key features and details
- Rabbit polyclonal to HIV1 p24
- Suitable for: WB, ELISA
- Reacts with: Human immunodeficiency virus
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-HIV1 p24抗体
参阅全部 HIV1 p24 一抗 -
描述
兔多克隆抗体to HIV1 p24 -
宿主
Rabbit -
经测试应用
适用于: WB, ELISAmore details -
种属反应性
与反应: Human immunodeficiency virus -
免疫原
Recombinant p24 protein over-expressed in E.coli using a plasmid carrying the Gag p24 coding region of HIV1 virus, subtype B.
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阳性对照
- Extract of MT4 cells infected with HIV-1 (LAI strain).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 6
Preservative: 0.09% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63913于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/2500. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).
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| ELISA |
Use at an assay dependent dilution.
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| 说明 |
|---|
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WB
1/2500. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa). |
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ELISA
Use at an assay dependent dilution. |
靶标
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相关性
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
细胞定位
Membrane -
数据库链接
- SwissProt: P04585 Human immunodeficiency virus
- SwissProt: P12497 Human immunodeficiency virus
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别名
- CA antibody
- Capsid protein p24 antibody
- HIV-1 Gag p24 antibody
see all
图片
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Western blot - Anti-HIV1 p24 antibody (ab63913)All lanes : Anti-HIV1 p24 antibody (ab63913) at 1/2500 dilution
Lane 1 : Extract of MT4 cells
Lane 2 : Extract of MT4 cells infected with HIV-1 (LAI strain)
Predicted band size: 24 kDa
Observed band size: 24 kDa
Bands at 41 and 55 kDa are also observed corresponding to HIV-p24 precursor proteins p41 and p55.
数据表及文件
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Datasheet download
文献 (23)
ab63913 被引用在 23 文献中.
- Pang H et al. Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane. Proc Natl Acad Sci U S A 120:e2212991120 (2023). PubMed: 36638209
- Wang S et al. Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity. Proc Natl Acad Sci U S A 119:N/A (2022). PubMed: 34987100
- Munoz O et al. Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells. PLoS Pathog 18:e1010673 (2022). PubMed: 35788752
- Zhao L et al. Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages. Nat Commun 12:3691 (2021). PubMed: 34140527
- Meuser ME et al. Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type-1 Capsid Inhibitor Using a Multistep Computational Workflow. J Med Chem 64:3747-3766 (2021). PubMed: 33750123
