Anti-HIV1 p24抗体(ab53841)
Key features and details
- Goat polyclonal to HIV1 p24
- Suitable for: ICC/IF, WB, IHC-Fr
- Reacts with: Human immunodeficiency virus
- Isotype: IgG
概述
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产品名称
Anti-HIV1 p24抗体
参阅全部 HIV1 p24 一抗 -
描述
山羊多克隆抗体to HIV1 p24 -
宿主
Goat -
特异性
ab53841 recognises the HIV1 viral capsid p24 protein encoded by the gag gene along with p6, p7 and p17 which provide structural elements of the virus. -
经测试应用
适用于: ICC/IF, WB, IHC-Frmore details -
种属反应性
与反应: Human immunodeficiency virus -
免疫原
Native p24, from strain IIIB
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Proprietary Purification -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53841于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use at an assay dependent concentration.
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| WB |
1/200 - 1/2000. Predicted molecular weight: 24 kDa.
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| IHC-Fr |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
ICC/IF
Use at an assay dependent concentration. |
|
WB
1/200 - 1/2000. Predicted molecular weight: 24 kDa. |
|
IHC-Fr
Use at an assay dependent concentration. |
靶标
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相关性
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
细胞定位
Membrane -
数据库链接
- SwissProt: P04585 Human immunodeficiency virus
- SwissProt: P12497 Human immunodeficiency virus
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别名
- CA antibody
- Capsid protein p24 antibody
- HIV-1 Gag p24 antibody
see all
实验方案
数据表及文件
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Datasheet download
文献 (10)
ab53841 被引用在 10 文献中.
- Gao L et al. Characterization and distribution of HIV-infected cells in semen. Emerg Microbes Infect 11:860-872 (2022). PubMed: 35253610
- Shytaj IL et al. Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress. EMBO Mol Med 13:e13901 (2021). PubMed: 34289240
- Drouin A et al. Escape of HIV-1 envelope glycoprotein from the restriction of infection by IFITM3. J Virol N/A:N/A (2020). PubMed: 33298540
- Lutgen V et al. HIV infects astrocytes in vivo and egresses from the brain to the periphery. PLoS Pathog 16:e1008381 (2020). PubMed: 32525948
- Peyret H et al. Covalent protein display on Hepatitis B core-like particles in plants through the in vivo use of the SpyTag/SpyCatcher system. Sci Rep 10:17095 (2020). PubMed: 33051543
- Gonzales B et al. Type I Phosphatidylinositol-4-Phosphate 5-Kinases a and ? Play a Key Role in Targeting HIV-1 Pr55Gag to the Plasma Membrane. J Virol 94:N/A (2020). PubMed: 32376619
- Quispe Calla NE et al. Exogenous oestrogen inhibits genital transmission of cell-associated HIV-1 in DMPA-treated humanized mice. J Int AIDS Soc 21:N/A (2018). PubMed: 29334191
- Suh HS et al. Evidence of the innate antiviral and neuroprotective properties of progranulin. PLoS One 9:e98184 (2014). WB . PubMed: 24878635
- Liu R et al. HIV Infection in gastric epithelial cells. J Infect Dis 208:1221-30 (2013). PubMed: 23852124
- Hughes AJ & Herr AE Microfluidic Western blotting. Proc Natl Acad Sci U S A : (2012). WB . PubMed: 23223527
