AB18975

Anti-Histone H2A 抗体

Anti-Histone H2A antibody

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(7 Publications)

Rabbit Polyclonal H2A antibody. Suitable for WB and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Human H2AC4 aa 1-50.

查看别名

H2AFM, HIST1H2AB, H2AC8, H2AFA, HIST1H2AE, H2AC4, Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m

1 Images

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Western blot - Anti-Histone H2A antibody (AB18975)

All lanes:

Western blot - Anti-Histone H2A antibody (ab18975) at 1 µg/mL

All lanes:

HeLa cell lysate

Predicted band size: 14 kDa

Observed band size: ~14 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

Synthetic Peptide within Human H2AC4 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P04908

特异性

ab18975 does not cross-react with other histones.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

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产品详情

This product is manufactured by BioVision, an Abcam company and was previously called 3621 Histone H2A Antibody.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

Preservative: 0.03% Proclin 300 Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA, 0.015% EDTA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

See full target information H2AC4

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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

BMC biology 22:188 PubMed39218869

2024

Identification of a novel DNA oxidative damage repair pathway, requiring the ubiquitination of the histone variant macroH2A1.1.

Applications

Unspecified application

Species

Unspecified reactive species

Khalid Ouararhni,Flore Mietton,Jamal S M Sabir,Abdulkhaleg Ibrahim,Annie Molla,Raed S Albheyri,Ali T Zari,Ahmed Bahieldin,Hervé Menoni,Christian Bronner,Stefan Dimitrov,Ali Hamiche

Cells 11: PubMed35741067

2022

CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.

Applications

Unspecified application

Species

Unspecified reactive species

Clarissa Braccia,Josie A Christopher,Oliver M Crook,Lisa M Breckels,Rayner M L Queiroz,Nara Liessi,Valeria Tomati,Valeria Capurro,Tiziano Bandiera,Simona Baldassari,Nicoletta Pedemonte,Kathryn S Lilley,Andrea Armirotti

STAR protocols 1:100178 PubMed33377072

2020

Protocol for Establishing Mouse Embryonic Stem Cells to Study Histone Inheritance Pattern at Single-Cell Resolution.

Applications

Unspecified application

Species

Unspecified reactive species

Binbin Ma,Tung-Jui Trieu,Shukry J Habib,Xin Chen

Aging 12:17099-17113 PubMed32915773

2020

Sirt6 is required for spermatogenesis in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Huafang Wei,Muhammad Babar Khawar,Wenhao Tang,Lina Wang,Liying Wang,Chao Liu,Hui Jiang,Wei Li

Cell reports 32:108003 PubMed32783931

2020

Differential Histone Distribution Patterns in Induced Asymmetrically Dividing Mouse Embryonic Stem Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Binbin Ma,Tung-Jui Trieu,Ji Cheng,Shuang Zhou,Qingsong Tang,Jing Xie,Ji-Long Liu,Keji Zhao,Shukry J Habib,Xin Chen

Nature communications 5:5323 PubMed25406515

2014

Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit.

Applications

Unspecified application

Species

Unspecified reactive species

Pavan Kumar Puvvula,Rohini Devi Desetty,Pascal Pineau,Agnés Marchio,Anne Moon,Anne Dejean,Oliver Bischof

Epigenetics & chromatin 6:7 PubMed23570311

2013

Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development.

Applications

Species

Unspecified reactive species

Kelly M Bush,Benjamin Tk Yuen,Bonnie L Barrilleaux,John W Riggs,Henriette O'Geen,Rebecca F Cotterman,Paul S Knoepfler

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Histone H2A 抗体

Anti-Histone H2A antibody

Western blot - Anti-Histone H2A antibody (AB18975)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

特异性