AB1764

Anti-Histone H2A (acetyl K5)抗体

Name: Histone H2A (acetyl K5)抗体 (ab1764)| Abcam中文官网
Brand: Abcam Limited
SKU: AB1764
Price: 4530 CNY
Availability: InStock
Rating: 4 (10 reviews)

Anti-Histone H2A (acetyl K5) antibody

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了解详情

(10 Reviews)

(13 Publications)

Rabbit Polyclonal H2A acetyl K5 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 13 publications. Immunogen corresponding to Synthetic Peptide within Human H2AC4 acetyl K5 conjugated to Ovalbumin.

查看别名

H2AFM, HIST1H2AB, H2AC8, H2AFA, HIST1H2AE, H2AC4, Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, H2AK5ac

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H2A (acetyl K5) antibody (AB1764)

IHC-P

Lab

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H2A (acetyl K5) antibody (AB1764)

IHC image of ab1764 staining Histone H2A (acetyl K5) in human colon formalin fixed paraffin embedded tissue sections, performed on a Leica Bond. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab1764, 1/1000 dilution, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. No primary antibody was used in the negative control (shown on the inset).

For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

IHC-P

applications

免疫原

Synthetic Peptide within Human H2AC4 acetyl K5 conjugated to Ovalbumin. The exact immunogen used to generate this antibody is proprietary information.

P04908

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "<p></p>" } } }

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产品详情

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

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性能和储存信息

形式

Liquid

纯度

Whole antiserum

存储溶液

Preservative: 0.02% Sodium azide

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

See full target information H2AC4 acetyl K5

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文献 (13)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 13:1611226 PubMed40530334

2025

Induced neural stem cells ameliorate blood-brain barrier injury by modulating the calcium signaling pathway of astrocyte in cerebral ischemia-reperfusion rats.

Applications

Unspecified application

Species

Unspecified reactive species

Xueyun Liang,Chuanshang Cao,Ningmei Liu,Dongmei Chen,Ting Liu,Haibin Ma,Jiaxin Liu,Taojuan Wu,Jianguo Niu

Epigenetics & chromatin 9:44 PubMed27777629

2016

An H4K16 histone acetyltransferase mediates decondensation of the X chromosome in males.

Applications

ICC/IF

Species

Unspecified reactive species

Alyssa C Lau,Kevin P Zhu,Elizabeth A Brouhard,Michael B Davis,Györgyi Csankovszki

eLife 5: PubMed27244239

2016

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.

Applications

Species

Unspecified reactive species

Kotaro Shirakawa,Lan Wang,Na Man,Jasna Maksimoska,Alexander W Sorum,Hyung W Lim,Intelly S Lee,Tadahiro Shimazu,John C Newman,Sebastian Schröder,Melanie Ott,Ronen Marmorstein,Jordan Meier,Stephen Nimer,Eric Verdin

Nature medicine 21:1154-62 PubMed26390242

2015

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Applications

Unspecified application

Species

Unspecified reactive species

Sang-Won Min,Xu Chen,Tara E Tracy,Yaqiao Li,Yungui Zhou,Chao Wang,Kotaro Shirakawa,S Sakura Minami,Erwin Defensor,Sue Ann Mok,Peter Dongmin Sohn,Birgit Schilling,Xin Cong,Lisa Ellerby,Bradford W Gibson,Jeffrey Johnson,Nevan Krogan,Mehrdad Shamloo,Jason Gestwicki,Eliezer Masliah,Eric Verdin,Li Gan

Molecular cell 59:502-11 PubMed26212453

2015

An Interactive Database for the Assessment of Histone Antibody Specificity.

Applications

Unspecified application

Species

Unspecified reactive species

Scott B Rothbart,Bradley M Dickson,Jesse R Raab,Adrian T Grzybowski,Krzysztof Krajewski,Angela H Guo,Erin K Shanle,Steven Z Josefowicz,Stephen M Fuchs,C David Allis,Terry R Magnuson,Alexander J Ruthenburg,Brian D Strahl

Cell cycle (Georgetown, Tex.) 12:2033-41 PubMed23777805

2013

Zinc finger protein 668 interacts with Tip60 to promote H2AX acetylation after DNA damage.

Applications

Unspecified application

Species

Unspecified reactive species

Ruozhen Hu,Edward Wang,Guang Peng,Hui Dai,Shiaw-Yih Lin

Cell 148:335-48 PubMed22244452

2012

Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages.

Applications

Unspecified application

Species

Unspecified reactive species

Dominic Schmidt,Petra C Schwalie,Michael D Wilson,Benoit Ballester,Angela Gonçalves,Claudia Kutter,Gordon D Brown,Aileen Marshall,Paul Flicek,Duncan T Odom

PloS one 3:e3650 PubMed18985155

2008

Analysis of Myc-induced histone modifications on target chromatin.

Applications

ChIP

Species

Unspecified reactive species

Francesca Martinato,Matteo Cesaroni,Bruno Amati,Ernesto Guccione

Nature 452:492-6 PubMed18337721

2008

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.

Applications

Species

Human

Eriko Michishita,Ronald A McCord,Elisabeth Berber,Mitomu Kioi,Hesed Padilla-Nash,Mara Damian,Peggie Cheung,Rika Kusumoto,Tiara L A Kawahara,J Carl Barrett,Howard Y Chang,Vilhelm A Bohr,Thomas Ried,Or Gozani,Katrin F Chua

FEBS letters 581:5275-81 PubMed17961556

2007

Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation.

Applications

Species

Mouse

Sandra N Garcia,Bhakti M Kirtane,Andrej J Podlutsky,Olivia M Pereira-Smith,Kaoru Tominaga

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Histone H2A (acetyl K5)抗体

Anti-Histone H2A (acetyl K5) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H2A (acetyl K5) antibody (AB1764)