Anti-Histone H1oo抗体(ab71580)
Key features and details
- Rabbit polyclonal to Histone H1oo
- Suitable for: IHC-P, WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-Histone H1oo抗体 -
描述
兔多克隆抗体to Histone H1oo -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide corresponding to Mouse Histone H1oo (C terminal).
Database link: Q8VIK3 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab71580于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use at an assay dependent concentration.
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
靶标
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功能
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. -
组织特异性
Oocyte-specific. -
序列相似性
Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain. -
细胞定位
Cytoplasm. Nucleus. Chromosome. - Information by UniProt
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数据库链接
- Entrez Gene: 171506 Mouse
- SwissProt: Q8VIK3 Mouse
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别名
- H1 histone family member O oocyte specific antibody
- H1FOO antibody
- H1FOO_HUMAN antibody
see all
数据表及文件
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Datasheet download
文献 (4)
ab71580 被引用在 4 文献中.
- Ruihuan G et al. Oocyte Vitrification Temporarily Turns on Oxidation-Reduction Process Genes in Mouse Preimplantation Embryos. Reprod Sci 28:1307-1315 (2021). PubMed: 33067752
- Li Z et al. Huangqi decoction inhibits hyperglycemia-induced podocyte apoptosis by down-regulated Nox4/p53/Bax signaling in vitro and in vivo. Am J Transl Res 11:3195-3212 (2019). PubMed: 31217889
- Funaya S et al. Linker histone H1FOO regulates the chromatin structure in mouse zygotes. FEBS Lett 592:2414-2424 (2018). PubMed: 29963710
- Hou J et al. Liraglutide, a long-acting GLP-1 mimetic, and its metabolite attenuate inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab 32:2201-10 (2012). PubMed: 22968320
