Anti-HEXIM1抗体[2416C2a] (ab58624)
![Western blot - Anti-HEXIM1 antibody [2416C2a] (ab58624)](https://www.abcam.cn/ps/products/58/ab58624/Images/ab58624-72533-anti-hexim1-antibody-2416c2a-western-blot.gif "Western blot - Anti-HEXIM1 antibody [2416C2a] (ab58624)")
Key features and details
- Mouse monoclonal [2416C2a] to HEXIM1
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
概述
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产品名称
Anti-HEXIM1抗体[2416C2a]
参阅全部 HEXIM1 一抗 -
描述
小鼠单克隆抗体[2416C2a] to HEXIM1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Recombinant fragment of human HEXIM1
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.0225% Potassium chloride, 0.03% Potassium phosphate, 0.1312% Sodium phosphate, 0.812% Sodium chloride, 1% BSA -
Concentration information loading... -
纯度
Protein G purified -
纯化说明
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane. -
克隆
单克隆 -
克隆编号
2416C2a -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab58624于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa.
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| 说明 |
|---|
|
WB
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa. |
靶标
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功能
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. -
组织特异性
Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. -
序列相似性
Belongs to the HEXIM family. -
结构域
The coiled-coil domain mediates oligomerization. -
细胞定位
Nucleus. Cytoplasm. Binds alpha-importin and is mostly nuclear. - Information by UniProt
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别名
- Cardiac lineage protein 1 antibody
- CLP 1 antibody
- CLP1 antibody
see all
图片
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Western blot - Anti-HEXIM1 antibody [2416C2a] (ab58624)Anti-HEXIM1 antibody [2416C2a] (ab58624) + immunogen (recombinant pfragment)
Predicted band size: 41 kDa
The MW is low because the recombinant fragment used as immunogen, rather than the full length protein, was used as positive control
数据表及文件
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Datasheet download
文献 (0)
ab58624 尚未被引用在任何文献中。
