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Microbiology Organism Virus RNA Virus ssRNA positive strand virus Hepatitis A/C/E/G

抗丙型肝炎病毒抗体(ab1035)

  • Datasheet
  • SDS
Submit a review Q&A (1)References (2)

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Key features and details

  • Rabbit polyclonal to Hepatitis C Virus
  • Suitable for: WB
  • Reacts with: Hepatitis C virus
  • Isotype: unknown

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概述

  • 产品名称

    抗丙型肝炎病毒抗体
    参阅全部 Hepatitis C Virus 一抗
  • 描述

    兔多克隆抗体to丙型肝炎病毒
  • 宿主

    Rabbit
  • 特异性

    This antibody reacts with the 44 kD core protein C3, the envelope protein, and E2 (NS1) of Hepatitis C Virus.
  • 经测试应用

    适用于: WBmore details
  • 种属反应性

    与反应: Hepatitis C virus
  • 免疫原

    Peptide corresponding to amino acids 33-43 of Hepatitis C Virus (HCV) core protein C3.

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液

    pH: 7.4
    Preservative: 0.05% Sodium azide
  • Concentration information loading...
  • 纯度

    Immunogen affinity purified
  • 克隆

    多克隆
  • 同种型

    unknown
  • 轻链类型

    unknown
  • 研究领域

    • Microbiology
    • Organism
    • Virus
    • RNA Virus
    • ssRNA positive strand virus
    • Hepatitis A/C/E/G

相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Recombinant Protein

    • Recombinant Human Hepatitis C Virus (mutated D168V) protein (ab198068)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab1035于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
WB
1/500 - 1/1000.
说明
WB
1/500 - 1/1000.

靶标

  • 相关性

    Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
  • 细胞定位

    Virus surface
  • 数据库链接

    • Entrez Gene: 951475 Hepatitis C virus
    • SwissProt: P27958 Hepatitis C virus
    • 别名

      • Genome polyprotein antibody
      • HCV antibody
      • Hepatitis C virus polyprotein antibody

    实验方案

    • Western blot protocols

    Click here to view the general protocols

    数据表及文件

    • SDS download

    • Datasheet download

      Download

    文献 (2)

    发表研究结果有使用 ab1035?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab1035 被引用在 2 文献中.

    • Munjal C  et al. TGF-ß mediates early angiogenesis and latent fibrosis in an Emilin1-deficient mouse model of aortic valve disease. Dis Model Mech 7:987-96 (2014). IHC . PubMed: 25056700
    • Yuk CS  et al. Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus. Biotechnol Lett 26:1563-8 (2004). PubMed: 15604797

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    Question

    I am searching for an antibody to Hepatitis C strain 2a for use with Western blotting. I see that you have several HCV antibodies but could only find information regarding which strain they were raised against for a few. An HCV core protein antibody may be suitable from another strain if it can be used in Western blotting assays but one specifically raised against strain 2a would be best. I would appreciate any further information you might be able to provide and thank you in advance for your time and consideration.

    Read More

    Abcam community

    Verified customer

    Asked on Mar 13 2006

    Answer

    Thank you for your enquiry. I looked up some Hepatitis C Virus antibodies that may be of interest to you and the information is listed below. It does not appear that we have one that is specific for strain 2a or has even bee tested for reactivity with that strain. Please contact us again if you have any additional questions. Ab20773 - Goat polyclonal to Hepatitis C Virus NS5: Immunogen used was recombinant NS5 a&b genotype 1a (100% of a and 70% of b). This antibody has not been tested for reactivity to genotype 2a. Ab1035 - Rabbit polyclonal to Hepatitis C Virus: Immunogen used was a peptide corresponding to amino acids 33-43 of Hepatitis C Virus (HCV) core protein C3. Ab1033 - Rabbit polyclonal to Hepatitis C Virus: Immunogen used was a peptide corresponding to amino acids 9-21 of Hepatitis C Virus (HCV) core protein C1. For ab1035 and ab1033, strain 2a hasn't been tested, but the understanding is that the sequences derived from core proteins C1 and C3 which were used for immunization are well conserved in the different strains of Hepatitis C virus. Therefore, it is likely that these antibodies will react with Hepatitis C strain 2a. Ab18662 - Mouse monoclonal [24-8 ] to Hepatitis C Virus: Immunogen used was a highly antigenic polypeptide consisting of essential sequences of at least 60 residues in length, which were selected from genes encoding the NS-3 region of Chinese HCV strains. This antibody is not hepatitis C virus[HCV] strain specific, and will recognize the NS3 of HCV strains. If the NS3 variation has been observed in this strain, it may cause the weaker/or non reaction when using this antibody, in the case of the variation is matched the epitope region or interfered the Antibody-Antigen binding-reaction site/sequences. Ab27791 - Goat polyclonal to Hepatitis C Virus: Immunogen used was recombinant chimeric HCV polyprotein (60 kDa). This antibody product will react with various HCV, and the reaction is not HCV strain specific.

    Read More

    Abcam Scientific Support

    回复于 Mar 16 2006

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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