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AB27711

Anti-Hemopexin抗体[32]

Anti-Hemopexin antibody [32]

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Mouse Monoclonal Hemopexin antibody. Suitable for sELISA and reacts with Human samples. Immunogen corresponding to Native Full Length Protein corresponding to Human Hemopexin.

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Hemopexin, Beta-1B-glycoprotein, HPX

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Sandwich ELISA - Anti-Hemopexin antibody [32] (AB27711)
  • sELISA

Unknown

Sandwich ELISA - Anti-Hemopexin antibody [32] (AB27711)

Standard Curve for Hemopexin (Analyte : Hemopexin protein (ab98988)); dilution range 1pg/ml to 1μg/ml using Capture Antibody Mouse monoclonal [32] to Hemopexin (ab27711) at 5μg/ml and Detector Antibody Rabbit polyclonal to Hemopexin (ab48135) at 0.5μg/ml.

不同偶联物与剂型 (1)

  • Biotin

    Biotin Anti-Hemopexin antibody [32]

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

32

亚型

IgG1

轻链类型

kappa

不含载体蛋白

No

反应种属

Human

应用

sELISA

applications

免疫原

Native Full Length Protein corresponding to Human Hemopexin.

P02790

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "5 µg/mL", "sELISA-species-notes": "<p>For sandwich ELISA, use this antibody as Capture at 5 µg/ml with Rabbit polyclonal to Hemopexin (<a href='/products/primary-antibodies/hemopexin-antibody-ab48135'>ab48135</a>) as Detection.</p>" } } }
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我们建议您务必查阅产品说明书，以确认其是否符合您的实验需求；若有疑问，也可联系我们的技术团队获取协助。

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产品详情

The fusion partner for this antibody is SP2mIL6.
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: 2.9% Sodium chloride, 0.0268% PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Hemopexin also known as HPX is a glycoprotein that transports heme in the blood. It has a molecular weight of approximately 57 kDa and is primarily expressed in the liver. Hemopexin binds to free heme with high affinity which prevents oxidative damage and conserves iron. It transports the heme to hepatocytes for breakdown and recycling protecting cells from iron-mediated toxicity and oxidative stress.
Biological function summary

The hemopexin function relates to protecting tissues from the harmful effects of free heme. Hemopexin does not work as part of a complex in this process but mainly acts independently. Its high binding affinity plays an important role in maintaining heme homeostasis in the plasma and tissues. By controlling heme levels hemopexin supports overall cellular health and function.

Pathways

The hemopexin molecular weight allows it to fit effectively within the heme metabolism and iron recycling pathways. This protein plays a significant role by delivering heme to the liver and facilitating its degradation by heme oxygenase. Hemopexin interacts closely with heme oxygenase and albumin two proteins important for the management of heme and iron levels in the body.

Several hemopexin functions contribute to the understanding of conditions such as hemolytic anemia and acute liver injury. In hemolytic anemia hemopexin helps mitigate the effects of increased heme levels due to excessive red blood cell breakdown. In the context of liver injury the protein assists in the detoxification process and supports hepatic function. Hemopexin-related proteins such as heme oxygenase link these diseases to hemopexin by their roles in managing oxidative stress and heme catabolism.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
See full target information Hemopexin
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详情请参阅我们的条款与条件。
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