Anti-Helicobacter pylori抗体(ab7788)
Key features and details
- Rabbit polyclonal to Helicobacter pylori
- Suitable for: IHC-P
- Reacts with: Helicobacter pylori
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-Helicobacter pylori抗体
参阅全部 Helicobacter pylori 一抗 -
描述
兔多克隆抗体to Helicobacter pylori -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Helicobacter pylori -
免疫原
Tissue, cells or virus corresponding to Helicobacter pylori. Purified helicobacter pylori.
-
常规说明
This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
Primary antibody说明
This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
Prolonged fixation in buffered formanlin may destroy the epitope. |
| 说明 |
|---|
|
IHC-P
1/100. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. Prolonged fixation in buffered formanlin may destroy the epitope. |
靶标
-
相关性
The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations. -
别名
- H. pylori antibody
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Helicobacter pylori antibody (ab7788)ab7788 stainning formalin-fixed/ paraffin-embbeded human stomach tissue sections infected with Helicobacter pylori.
数据表及文件
-
SDS download
-
Datasheet download
文献 (8)
ab7788 被引用在 8 文献中.
- Wang X et al. Helicobacter pylori inhibits autophagic flux and promotes its intracellular survival and colonization by down-regulating SIRT1. J Cell Mol Med 25:3348-3360 (2021). PubMed: 33641223
- Dangtakot R et al. CagA+ Helicobacter pylori infection and N-nitrosodimethylamine administration induce cholangiocarcinoma development in hamsters. Helicobacter 26:e12817 (2021). PubMed: 34031944
- Xie C et al. Inhibition of autophagy aggravates DNA damage response and gastric tumorigenesis via Rad51 ubiquitination in response to H. pylori infection. Gut Microbes 11:1567-1589 (2020). PubMed: 32588736
- Hu W et al. Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells. Autophagy 15:707-725 (2019). PubMed: 30612517
- Dangtakot R et al. Coinfection with Helicobacter pylori and Opisthorchis viverrini Enhances the Severity of Hepatobiliary Abnormalities in Hamsters. Infect Immun 85:N/A (2017). PubMed: 28138021
- Itthitaetrakool U et al. Chronic Opisthorchis viverrini Infection Changes the Liver Microbiome and Promotes Helicobacter Growth. PLoS One 11:e0165798 (2016). IHC-P . PubMed: 27806126
- Li ZW et al. Inflammatory cytokine gene polymorphisms increase the risk of atrophic gastritis and intestinal metaplasia. World J Gastroenterol 16:1788-94 (2010). IHC-P . PubMed: 20380014
- Shin CM et al. Validation of diagnostic tests for Helicobacter pylori with regard to grade of atrophic gastritis and/or intestinal metaplasia. Helicobacter 14:512-9 (2009). PubMed: 19889068