Anti-hCG抗体(ab54410)
Key features and details
- Rabbit polyclonal to hCG
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-hCG抗体
参阅全部 hCG 一抗 -
描述
兔多克隆抗体to hCG -
宿主
Rabbit -
特异性
This antibody recognises both alpha and beta subunits of hCG. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Purified Chorionic Gonadotropin from human placental glucoprotein urine.
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阳性对照
- Purified human CG and rat liver tissue lysate.
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 5778 Chorionic Gonadotropin (CG) Antibody. 5778-100 is the same size as the 100 µg size of ab54410.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.5% BSA, 30% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab54410于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 4 µg/ml.
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| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 4 µg/ml. |
靶标
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相关性
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 1081 Human
- Entrez Gene: 1082 Human
- Omim: 118850 Human
- Omim: 118860 Human
- SwissProt: P01215 Human
- SwissProt: P01233 Human
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别名
- anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG alpha antibody
- CG-ALPHA antibody
see all
图片
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Western blot - Anti-hCG antibody (ab54410)All lanes : Anti-hCG antibody (ab54410) (0.5-4 ug/m)
Lane 1 : Recombinant Human Chorionic Gonadotropin at 0.01 µg
Lane 2 : Recombinant Human Chorionic Gonadotropin at 0.05 µg
Lane 3 : Recombinant Human Chorionic Gonadotropin at 0.25 µg
Lane 4 : Recombinant Human Chorionic Gonadotropin at 1 µgThis information is only intended as a guide. The optimal dilutions must be determined by the user.
数据表及文件
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SDS download
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Datasheet download
文献 (9)
ab54410 被引用在 9 文献中.
- Mahr RM et al. Mitochondrial citrate metabolism and efflux regulate BeWo differentiation. Sci Rep 13:7387 (2023). PubMed: 37149697
- Zhu H et al. NPFF increases fusogenic proteins syncytin 1 and syncytin 2 via GCM1 in first trimester primary human cytotrophoblast cells. FASEB J N/A:N/A (2020). PubMed: 32501590
- Hong G et al. New photothermal immunoassay of human chorionic gonadotropin using Prussian blue nanoparticle-based photothermal conversion. Anal Bioanal Chem 411:6837-6845 (2019). PubMed: 31471682
- Lu X et al. Twist1 is involved in trophoblast syncytialization by regulating GCM1. Placenta 39:45-54 (2016). PubMed: 26992674
- Li Y et al. Involvement of nephrin in human placental trophoblast syncytialization. Reproduction 149:339-46 (2015). PubMed: 25614620
- Zhou Z et al. The cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression during human trophoblast syncytialization. Placenta 35:907-18 (2014). PubMed: 25175744
- Wang R et al. Live cell imaging of in vitro human trophoblast syncytialization. Biol Reprod 90:117 (2014). PubMed: 24740598
- Zhou Z et al. The proprotein convertase furin is required for trophoblast syncytialization. Cell Death Dis 4:e593 (2013). WB ; Human . PubMed: 23598405
- Dukic-Stefanovic S et al. Chorionic gonadotropin and its receptor are both expressed in human retina, possible implications in normal and pathological conditions. PLoS One 7:e52567 (2012). WB ; Human . PubMed: 23285091