AB106720

Anti-Growth Hormone 抗体 [KT19]

Name: Growth Hormone抗体[KT19] (ab106720)| Abcam中文官网
Brand: Abcam Limited
SKU: AB106720
Price: 4829 CNY
Availability: InStock

Anti-Growth Hormone antibody [KT19]

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(1 Publication)

Rat Monoclonal Growth Hormone antibody. Suitable for sELISA and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GH1.

查看别名

Somatotropin, Growth hormone, Growth hormone 1, Pituitary growth hormone, GH, GH-N, GH1

1 Images

Sandwich ELISA - Anti-Growth Hormone antibody [KT19] (AB106720)

sELISA

Unknown

Sandwich ELISA - Anti-Growth Hormone antibody [KT19] (AB106720)

Sandwich ELISA using ab106720 at 5 μg/ml as capture antibody and an HRP conjugated detection antibody.

关键信息

宿主种属

Rat

克隆

Monoclonal

克隆号

KT19

亚型

IgG1

不含载体蛋白

反应种属

Human

应用

sELISA

applications

免疫原

Recombinant Full Length Protein corresponding to Human GH1.

P01241

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "5 µg/mL", "sELISA-species-notes": "<p>Can be used as Capture antibody when paired with <a href='/products/primary-antibodies/hrp-growth-hormone-antibody-kt34-ab106749'>ab106749</a>.</p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein G

存储溶液

Preservative: 0.1% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Growth Hormone (GH) also known as somatotropin is a polypeptide hormone with a mass of approximately 22 kDa. The pituitary gland synthesizes and secretes GH. Once synthesized GH circulates in the bloodstream and affects various tissues throughout the body. GH's expression is tightly regulated because of its significant roles in growth processes. Researchers might use anti-growth hormone antibodies and various hGH testing kits including ELISA to study its levels and functions.

Biological function summary

GH triggers growth and cell reproduction by exerting effects on multiple tissues. It binds to the growth hormone receptor which initiates a cascade of reactions that ultimately stimulates growth in muscle bone and cartilage. GH also contributes to protein synthesis and helps regulate metabolism. GH acts mostly independently but can interact with cytokines and other hormones.

Pathways

GH plays important roles in the regulation of the JAK-STAT signaling pathway and the IGF-1 signaling pathway. The JAK-STAT pathway is important for transmitting the signal of GH binding to its receptor into cellular responses. GH stimulates IGF-1 production in the liver and IGF-1 then acts in an endocrine manner to mediate much of GH’s growth-promoting activity. These interactions highlight the interconnectedness of GH with other hormones in growth signaling networks.

Several health conditions can arise from abnormal levels of GH. Dwarfism occurs due to GH deficiency while acromegaly results from GH excess. Clinical analysis might use hGH kits to measure hormone levels and aid in diagnosis. GH's role in such conditions links it to other hormones like insulin and glucagon that help regulate glucose levels further affecting metabolic processes. Recombinant forms of GH are used in therapy for these disorders providing avenues for treatment and management.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

See full target information GH1

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

BMC pharmacology & toxicology 23:92 PubMed36476246

2022

Morphine suppresses the immune function of lung cancer by up-regulating MAEL expression.

Applications

Unspecified application

Species

Unspecified reactive species

Qichao Wang,Zhenfu Liu,Shuhong Tang,Zhen Wu

View all publications

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Anti-Growth Hormone 抗体 [KT19]

Anti-Growth Hormone antibody [KT19]

Sandwich ELISA - Anti-Growth Hormone antibody [KT19] (AB106720)

关键信息

宿主种属

克隆

克隆号

亚型

不含载体蛋白

反应种属

应用

免疫原