为了使您在Abcam官网的浏览体验更顺畅,请使用最新版本的浏览器比如 Google Chrome

Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online
致电 +86 21 2070 0500 或 联系我们

  • 我的账户
  • 退出
登录 或 注册

欢迎光临

登录 或

您还没有帐户?

注册
我的购物篮
快速订购
Abcam homepage

  • 研究用途的产品
    按产品类型
    一抗
    二抗
    免疫测定试剂盒与试剂
    细胞与组织成像工具
    细胞与生化测定
    按产品类型
    蛋白质与肽
    蛋白质组学工具
    激动剂、活化剂、拮抗剂与抑制剂
    细胞株和裂解液
    多因子分析试剂盒
    按研究领域
    癌症
    心血管
    细胞生物学
    表观遗传学
    代谢
    发育生物学
    按研究领域
    免疫学
    微生物学
    神经科学
    信号转导
    干细胞
  • 定制化产品 & 合作关系
    定制化产品 & 合作关系

    定制化产品和商务合作加速您的诊断和治疗项目

    定制化产品

    与我们成为伙伴

  • 技术支持
    支持中心

    获取研究建议和支持

    查看支持中心

    Protocols

    一步一步完成您的实验

    查看Protocols

  • 活动通知
    • 会议年历
    • 肿瘤研究
    • 心血管研究
    • 染色质及细胞核信号转导研究
    • 免疫学
    • 神经生物学
    • 干细胞研究
    • 商品展览
    • 实验技术视频
    查看最新活动

    活动说明、摘要提交、演讲者、注册方式及更多信息

    查看全球活动安排

  • 通路
    细胞信号转导通路

    查看所有通路

    查看交叉通路

Neuroscience Cell Type Marker Neuron marker Growth Cone

Anti-Growth Cone抗体[2G13] (ab7762)

  • Datasheet
Reviews (1)Q&A (3)References (4)

Product price, shipping and contact information

Currently unavailable

抱歉,我们目前无法显示此内容。

请联系我们以完成下单,或者之后再尝试访问。

 

正在加载规格和价格。。。

 

送货和订单信息

运输费用

Promotion Information

Abpromise

产品质量保证,客户专家支持,

点击获取更多

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Growth Cone antibody [2G13] (ab7762)

    Key features and details

    • Mouse monoclonal [2G13] to Growth Cone
    • Suitable for: WB, IHC-Fr, ICC/IF, IHC-P
    • Reacts with: Mouse, Rat, Chicken
    • Isotype: IgM

    你可能会感兴趣

    肽
    Product image
    Mouse Myelin Basic Protein peptide (ab40389)
    一抗
    Product image
    Anti-GABA B Receptor 2/GABBR2 antibody [EP2411Y] (ab75838)
    一抗
    Product image
    Anti-160 kD Neurofilament Medium antibody [NF-09] - Neuronal Marker (ab7794)

    查看更多相关产品

    概述

    • 产品名称

      Anti-Growth Cone抗体[2G13]
    • 描述

      小鼠单克隆抗体[2G13] to Growth Cone
    • 宿主

      Mouse
    • 经测试应用

      适用于: WB, IHC-Fr, ICC/IF, IHC-Pmore details
      不适用于: Flow Cyt
    • 种属反应性

      与反应: Mouse, Rat, Chicken
    • 免疫原

      Tissue, cells or virus corresponding to Chicken Growth Cone. Embryonic chick tectal membranes

    • 常规说明

      This antibody is useful as a general reagent for the detection of axonal growth cones in tissue sections and potentially a key marker in neuronal development research.

       

      This antibody recognises an intracellular protein 2G13p which is restricted to growth cones in developing brain and embryonic neurons in culture. The protein 2G13p also appears to be associated with filamentous actin in the growth cones suggesting a role for 2G13p in growth cone motility. This antibody is suitable for use in immunohistological studies of both frozen and paraffin-embedded sections, staining growth cones, including their filopodia and lamellipodies.

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid
    • 存放说明

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
    • Concentration information loading...
    • 纯度

      Tissue culture supernatant
    • Primary antibody说明

      This antibody recognises an intracellular protein 2G13p which is restricted to growth cones in developing brain and embryonic neurons in culture. The protein 2G13p also appears to be associated with filamentous actin in the growth cones suggesting a role for 2G13p in growth cone motility. This antibody is suitable for use in immunohistological studies of both frozen and paraffin-embedded sections, staining growth cones, including their filopodia and lamellipodies.
    • 克隆

      单克隆
    • 克隆编号

      2G13
    • 骨髓瘤

      NS1
    • 同种型

      IgM
    • 研究领域

      • Neuroscience
      • Cell Type Marker
      • Neuron marker
      • Growth Cone
      • Tags & Cell Markers
      • Cell Type Markers
      • Neuroscience Markers
      • Growth Cone marker

    相关产品

    • Compatible Secondaries

      • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
      • Goat Anti-Mouse IgM H&L (ab9167)

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab7762于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    Use at an assay dependent concentration.
    IHC-Fr
    Use at an assay dependent concentration.
    ICC/IF (1)
    Use at an assay dependent concentration.
    IHC-P
    1/4.

    This product does not require protein digestion pre-treatment sections e.g. trypsin or pronase, and does not require antigen retrieval using heat treatment prior to staining.

    说明
    WB
    Use at an assay dependent concentration.
    IHC-Fr
    Use at an assay dependent concentration.
    ICC/IF
    Use at an assay dependent concentration.
    IHC-P
    1/4.

    This product does not require protein digestion pre-treatment sections e.g. trypsin or pronase, and does not require antigen retrieval using heat treatment prior to staining.

    应用说明
    Is unsuitable for Flow Cyt.

    靶标

    • 相关性

      Growth cones are specialised sensory structures located at the tip of neurites which are involved in the mechanism that enable elongation and navigation of axons during neuronal development.

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Growth Cone antibody [2G13] (ab7762)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Growth Cone antibody [2G13] (ab7762)

      Immunohistochemical staining of growth cones of primary olfactory neurons within the olfactory bulb in the developing rat brain using ab7762.

    实验方案

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    数据表及文件

    • Datasheet download

      Download

    文献 (4)

    发表研究结果有使用 ab7762?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab7762 被引用在 4 文献中.

    • Smith LK  et al. Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism. PLoS One 16:e0248309 (2021). PubMed: 33705493
    • Kumar H  et al. Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury. J Neurosci 40:1943-1955 (2020). PubMed: 31974206
    • Wülfing C & Günther HS Dendritic cells and macrophages neurally hard-wired in the lymph node. Sci Rep 5:16866 (2015). PubMed: 26581550
    • Stettler O  et al. Monoclonal antibody 2G13, a new axonal growth cone marker. J Neurocytol 28:1035-44 (1999). PubMed: 11054903

    客户评价及客户问答

    Show All 评价 Q&A
    提交评价 提交问题

    1-4 of 4 Abreviews or Q&A

    Immunocytochemistry/ Immunofluorescence abreview for Anti-Growth Cone antibody [2G13]

    Good
    Abreviews
    Abreviews
    abreview image
    Application
    Immunocytochemistry/ Immunofluorescence
    Sample
    Rat Cell (Primary (E18) hippocampal & spinal neurons)
    Permeabilization
    Yes - 0.2% Triton X100 in PBS, 30'
    Specification
    Primary (E18) hippocampal & spinal neurons
    Blocking step
    BSA as blocking agent for 3 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Fixative
    Paraformaldehyde
    Read More
    The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

    DR. Alan Howe

    Verified customer

    提交于 Aug 14 2007

    Question

    What starting dilution should I use for IF with this antibody?

    Read More

    Abcam community

    Verified customer

    Asked on Mar 21 2006

    Answer

    Thank you for your enquiry. We would recommend a starting dilution of 1:4 for ab7762 in IHC. I hope this information helps. Please do not hesitate to contact us again if you need any further information.

    Read More

    Abcam Scientific Support

    回复于 Mar 22 2006

    Question

    What is the MW?

    Read More

    Abcam community

    Verified customer

    Asked on Jan 21 2005

    Answer

    In Western blotting the antibody has been shown to recognize a protein of approximately 48 kDa.

    Read More

    Abcam Scientific Support

    回复于 Jan 25 2005

    Question

    Is there published literature using this antibody in tissue sections as immunohistochemical stain?

    Read More

    Abcam community

    Verified customer

    Asked on Jan 10 2002

    Answer

    The only published literature that we are aware of, apart from our antibody data sheet, is:
    Stettler O., Bush, M. S., Kasper, M., Schlosshauer, B. and Gordon-Weeks, P. R. 1999. Monoclonal antibody 2G13, a new axonal growth cone marker. J Neurocytol. 28:1035-1044.

    Read More

    Abcam Scientific Support

    回复于 Jan 10 2002

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    通过邮件收到学术资源和促销信息 注册
    研究类别(A-Z)
    • 肿瘤研究
    • 心血管研究
    • 细胞生物学
    • 发育生物学
    • 染色质及细胞核信号转导研究
    • 免疫学
    • 代谢
    • 微生物学
    • 神经生物学
    • 信号转导研究
    • 干细胞研究
    产品种类(A-Z)
    • 一抗
    • 二抗
    • 生化试剂
    • 亚类对照
    • 流式细胞仪多色选择器
    • 试剂盒
    • 内参对照
    • 细胞裂解液
    • 多肽
    • 蛋白酶
    • 组织切片
    • 蛋白标签及细胞标记物
    • 相关试剂及工具
    帮助与支持
    • 技术支持
    • 技术FAQ
    • 实验步骤与建议
    • 购买FAQ
    • RabMAb 产品
    • 培训课程
    • 按靶标浏览
    企业
    • 企业资讯
    • 投资者关系
    • 公司新闻
    • 招贤纳士
    • 关于我们
    活动通知
    • 商品展览
    • 会议
    全球网站
    • abcam.com
    • abcam.co.jp
    QR code for Weechat

    微信扫码 关注我们

    沪ICP备14046373号-1

    沪公网安备 31011502007413号

    • 销售条款
    • 网站使用条款
    • Cookie政策
    • 隐私权政策
    • 法律
    © 1998-2025 艾博抗(上海)贸易有限公司版权所有