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AB128234

Anti-Gr28b抗体

Anti-Gr28b antibody

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(1 Publication)

Rabbit Polyclonal GR28B antibody. Suitable for WB, ELISA and reacts with Drosophila melanogaster samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Drosophila melanogaster Gr28b.

查看别名

CG13788, Gr28b, Putative gustatory receptor 28b

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Drosophila melanogaster

应用

WB, ELISA

applications

免疫原

Synthetic Peptide within Drosophila melanogaster Gr28b. The exact immunogen used to generate this antibody is proprietary information.

Q9VM08

特异性

ab128234 reacts with Drosophila melanogaster Gr28b isoform B.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Drosophila melanogaster": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Gr28b also known as Gustatory receptor 28b functions mechanically as a gustatory receptor in Drosophila melanogaster. This receptor weighs approximately 37 kDa and is primarily expressed in sensory neurons particularly in the labellum and tarsi. Gr28b's role involves detecting specific chemical stimuli contributing to the fly's ability to respond to various taste cues.
Biological function summary

This receptor plays a role in taste perception and chemosensory processes within the gustatory system of Drosophila. Gr28b is not a part of any larger protein complex but operates as a single unit within sensory neurons. It detects specific chemical components allowing the fly to discern between different food sources and potentially harmful substances.

Pathways

Gr28b contributes significantly to the gustation pathway within Drosophila which is critical for feeding behavior. This receptor works alongside other gustatory receptors in the fly such as Gr5a to mediate the detection of diverse tastants. Together these receptors integrate signals that modulate feeding decisions and other gustatory-driven behaviors.

Gr28b's functions in taste perception and feeding behaviors link to research on obesity and metabolic disorders in Drosophila models. While not directly associated with human diseases it serves as a model for understanding similar mechanisms in humans. Other proteins connected to these studies include insulin and its pathway components which influence metabolic processes influenced by taste perception.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression also suggests nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands.
See full target information Gr28b
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of clinical investigation 123:4525-39 PubMed24051377

2013

Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Theodore G Drivas,Erika L F Holzbaur,Jean Bennett
View all publications
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