Anti-GPR56抗体(ab172361)
Key features and details
- Rabbit polyclonal to GPR56
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-GPR56抗体
参阅全部 GPR56 一抗 -
描述
兔多克隆抗体to GPR56 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee, Macaque monkey, Gorilla, Orangutan
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免疫原
Recombinant full length protein within Human GPR56 aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: AAH08770.1 -
阳性对照
- GPR56 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172361于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa.
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| 说明 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa. |
靶标
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功能
Could be involved in cell-cell interactions. -
组织特异性
Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. -
疾病相关
Polymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry. -
序列相似性
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain. -
翻译后修饰
The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 737751 Chimpanzee
- Entrez Gene: 101141011 Gorilla
- Entrez Gene: 9289 Human
- Omim: 604110 Human
- SwissProt: Q50DM7 Chimpanzee
- SwissProt: Q50DM6 Gorilla
- SwissProt: Q9Y653 Human
- SwissProt: Q50DM5 Orangutan
see all -
别名
- 7 transmembrane protein with no EGF like N terminal domains 1 antibody
- BFPP antibody
- DKFZp781L1398 antibody
see all
图片
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Western blot - Anti-GPR56 antibody (ab172361)All lanes : Anti-Doublecortin antibody [EPR10936] (ab172631) at 1/1000 dilution
Lane 1 : GPR56 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 78 kDa
数据表及文件
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Datasheet download
文献 (3)
ab172361 被引用在 3 文献中.
- Nowicki A et al. The Effect of 3'-Hydroxy-3,4,5,4'-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells. Int J Mol Sci 21:N/A (2020). PubMed: 32046103
- Ackerman SD et al. GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med 215:941-961 (2018). PubMed: 29367382
- Song Y et al. Expression of G protein-coupled receptor 56 is associated with tumor progression in non-small-cell lung carcinoma patients. Onco Targets Ther 9:4105-12 (2016). WB, ELISA ; Human . PubMed: 27462165
