Anti-GPR177/WLS抗体(ab72385)
Key features and details
- Chicken polyclonal to GPR177/WLS
- Suitable for: WB
- Reacts with: Human
- Isotype: IgY
概述
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产品名称
Anti-GPR177/WLS抗体 -
描述
鸡多克隆抗体to GPR177/WLS -
宿主
Chicken -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein L purified -
克隆
多克隆 -
同种型
IgY -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab72385于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/2000 - 1/5000. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).
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| 说明 |
|---|
|
WB
1/2000 - 1/5000. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa). |
靶标
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功能
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. -
序列相似性
Belongs to the wntless family. -
细胞定位
Golgi apparatus membrane. Cytoplasmic vesicle membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 79971 Human
- Omim: 611514 Human
- SwissProt: Q5T9L3 Human
- Unigene: 647659 Human
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别名
- C1orf139 antibody
- DKFZp686I0788 antibody
- Evenness interrupted, Drosophila, homolg of antibody
see all
图片
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Western blot - Anti-GPR177/WLS antibody (ab72385)All lanes : Anti-GPR177/WLS antibody (ab72385) at 1/2000 dilution
Lane 1 : Molecular weight markers
Lane 2 : HEK293 cell lysate transfected with GPR177/WLS-GFP
Predicted band size: 62 kDa
Observed band size: 62 kDaThe HEK293 cell protein lysate contains both transfected GPR177/WLS-GFP fusion protein (75 kDa) and endogenous GPR177/WLS protein (~62 kDa).
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab72385 被引用在 4 文献中.
- Li Q et al. AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression. iScience 26:108523 (2023). PubMed: 38162032
- Jing J et al. Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis. Elife 10:N/A (2021). PubMed: 33480845
- Wang LT et al. WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism. Autophagy 17:4202-4217 (2021). PubMed: 33853474
- de Groot RE et al. Retromer dependent recycling of the wnt secretion factor wls is dispensable for stem cell maintenance in the Mammalian intestinal epithelium. PLoS One 8:e76971 (2013). WB ; Mouse . PubMed: 24130821